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Biomedical subjects

A Nadir

Publications and source records attributed to A Nadir.

25 records · Page 2Linked to original sources
PubMed1994

Gastrointestinal problems experienced in an intensive care unit.

Medical emergencies involving the gastrointestinal tract include bleeding, abdominal pain, diarrhea, toxic megacolon, pancreatitis, and hepatic failure. Each can be a cause for admission to an intensive care unit or occur de novo in a patient hospitalized in such a unit. The clinical presentation, management, and consequences of these varied gastrointestinal problems seen in an intensive care unit are presented followed by a recommended course of action.

Gastrointestinal Diseases↗
PubMed1994

Rheumatoid arthritis: a complication of interferon therapy.

A case report of rheumatoid arthritis developing during alpha-interferon therapy of chronic hepatitis C is reported. The rheumatoid arthritis was severe, being non-responsive to the use of nonsteroidal anti-inflammatory drugs, and persisted despite discontinuation of the interferon therapy. The literature relative to this case suggesting an association between rheumatoid arthritis and interferon therapy is presented. This case suggests that interferon therapy may precipitate subclinical rheumatoid arthritis in an individual without pre-existing clinical arthritis.

Adult↗
PubMed1994

Parental and medical over-administration of acetaminophen causing lethal hepatotoxicity in a 10-year-old.

A 10-year-old girl with acute influenza B virus disease was given repetitive doses of acetaminophen by her mother to reduce the child's fever. When finally seen by trained medical personnel, the child was experiencing abdominal pain, nausea, and vomiting, which are classic signs of acetaminophen hepatotoxicity. Despite these findings, the child was given additional acetaminophen and experienced lethal hepatotoxicity.

Acetaminophen↗
PubMedDate not supplied

Gastrointestinal complications of liver transplantation.

Liver transplantation (OLTx) has become a common procedure at many centers in Europe and North America. The 1 and 5 year survival of patients receiving liver transplants at most centers is 75-85% and 60-65% respectively. As such, many physicians, in addition to those at transplant centers, will be called upon to see and care for recipients surviving liver transplants. The gastrointestinal tract is a common site of post-transplantation problems. These problems involve all components of the gastrointestinal tract. Many have characteristic, if not unique, presentations and clinical courses. They are reviewed for the physician in clinical practice who does not practice at a transplant center.

Biliary Tract Diseases↗
PubMedDate not supplied

Liver transplantation after an acute episode of spontaneous bacterial peritonitis.

BACKGROUND/AIMS: Spontaneous bacterial peritonitis (SBP) is a common complication of advanced cirrhosis. Thus many potential transplant recipients will experience this problem while waiting for a liver donor. The minimal amount of time with the use of appropriate antibiotics after which a potential recipient can be transplanted safely is not currently known. We examined the effect of pretransplant SBP on subsequent post-transplant outcome. MATERIALS AND METHODS: A retrospective review of the records of 100 liver transplant recipients having an episode of spontaneous bacterial peritonitis within 30 days of their transplant was performed. The records of transplant controls without an episode of spontaneous bacterial peritonitis were reviewed to compare the outcome between the two groups in terms of sepsis during the initial 30 post-transplant days. RESULTS: Post-transplant sepsis occurred in 8.8% of the cases and 10% of the controls (NSO). Only one episode in the study group could be ascribed to the pre-transplant episode of spontaneous bacterial peritonitis and it occurred in an IgA deficient recipient. CONCLUSIONS: These data suggest that SBP prior to liver transplantation does not lead to an increased rate of postoperative sepsis if 4 or more days of appropriate treatment for SBP are administered prior to liver transplantation.

Acute Disease↗