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Biomedical subjects

A Novarini

Publications and source records attributed to A Novarini.

At least 145 records · Page 8Linked to original sources

[Post-acute long stay and extensive rehabilitation: study of the first year of work at a long stay university hospital unit].

Long stay is a new type of hospital admission geared to internal medicine patients requiring long-term stays in hospital and prolonged treatment for the purposes of stabilization or clinical rehabilitation. Given the lack of specific experience, we monitored the progress of a Long-Stay Unit with the aim to estimate the clinical and organizational impact. We studied 263 patients (59.3% females, 40.7% males; mean age 76.3 +/- 11.5 years, 42.2% all in their late eighties) coming from medical wards (75%) and from surgical wards (25%). The clinical complexity was prospectively estimated by a form divided into 3 sections: the first part was filled out at the time of transfer, the second part at set intervals throughout the period and the third at the end of the stay. Mean length of stay for medical patients was 33.2 days, for surgical patients 28.6 days (NS). Main transfer diagnosis: 50% of the patients fell into two diagnostic groups: malignant neoplasm (33.1%) and cerebral ictus (17.5%). Some data evidenced remarkable clinical complexity: 93.9% of the patients had one or more secondary diagnoses; when initially admitted 89.4% already presented with complications or serious outcomes; while in the Long-Stay Unit 83.3% required medical treatment and extensive nursing care; 87.1% had further major complications; 56.3% was totally dependent; 42.6% was totally bedridden and 35.4% died. In conclusion, the majority of long-stay patients in a medium-to-large polyclinic hospital present with several concomitant diseases, with extremely invalidating complaints, characterized over the short-to-mid term by serious clinical complications. They require a great deal of competent medical/nursing care as well as highly qualified internal medicine specialists.

Acute Disease↗

[Allergic bronchopulmonary aspergillosis; an important cause of asthma sometimes ignored].

The Authors describe a clinical case of allergic bronchopulmonary aspergillosis that remained unrecognized for a long time. The pathogenetic role of the environment, home climatology, and familiarity is considered. A possible therapeutic approach involving the use of associations of steroids and ketoconazole is also discussed. The Authors would like to draw the attention of physicians to forms of bronchial asthma with eosinophilia.

Adult↗

[Drug therapy of pheochromocytoma].

The Authors briefly review the clinical findings, the diagnostic biochemical procedures and the management of pheochromocytoma. The most recent pharmacological approaches with calcium-channel blockers or angiotensin-converting enzyme inhibitors are particularly discussed.

Adrenal Gland Neoplasms↗

[Physiopathological and clinical features of hypernatremia].

The observation of hypernatriaemia in a large series under a variety of clinical conditions (gastrointestinal loss, increased "forced loss", and insufficiency parenteral feeding) is made the occasional for an overview of its main physiopathological and clinical features. From the physiopathological standpoint, the syndrome is rarely coupled with an absolute water deficiency. More commonly, sodium and water losses go together to bring about a fall in both intracellular and extracellular volume. The clinical significance of hypernatriaemia is essentially linked to increased osmolar content, not only of the extracellular liquid, but more particularly (due to water depletion) of the intracellular compartment, which underlies the establishment and progress of the anatomopathological lesions and the clinical symptoms.

Adult↗