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Biomedical subjects

A O Ogunyemi

Publications and source records attributed to A O Ogunyemi.

13 recordsLinked to original sources

Occipital paroxysmal discharges suppressed by eye opening: variability in clinical and seizure manifestations in childhood.

The EEG in childhood epilepsy with occipital paroxysms (CEOP) was termed "distinctive" by Gastaut (1985) and Talwar et al. (1992) and "characteristic" by Herranz Tanarro et al. (1984), which suggests that the EEG is specific and diagnostic for CEOP. However, this hypothesis has been challenged (Newton and Aicardi, 1983; Beaumanoir and Grandjean, 1987). To test this, we reviewed 5,291 EEG reports made in 5 1/2 years in the only tertiary pediatric center in Newfoundland and Labrador. We identified 31 children who had one or more EEGs with occipital spike/sharp waves showing suppression of discharges with eye opening and normal background activity. Six had CEOP, 17 had benign nocturnal childhood occipital epilepsy, 5 had symptomatic epilepsy, 3 had unusual complex partial seizures (CPS), 4 had only provoked seizures, and 2 had no definite seizures. Overlap between seizure types was common. The EEG criteria for CEOP are not very specific.

Age Factors↗

Complex partial status epilepticus provoked by "crack" cocaine.

A 53-year-old woman with a history of chronic abuse of "crack" cocaine developed isolated complex partial status epilepticus after 3 days of frequent cocaine use. The electroencephalogram demonstrated focal epileptiform activity. Follow-up for 1 year during which she reported continuous abstinence from cocaine and anti-convulsants revealed no recurrence of seizures.

Cocaine↗

Validity of the GHQ-30 in a Nigerian medical outpatient clinic.

Basic mental health vital statistics are scarce in developing countries. Scarcer still are validated psychological survey instruments which can be used in these settings. A method of dealing with such scarcity is through the validation of instruments developed elsewhere. One such instrument is Goldberg GHQ-30. The 30-item General Health Questionnaire was used by the authors as a screening instrument for emotional disorder in a general medical outpatient clinic. The GHQ-30 misclassified 32.3% of the respondents, a majority of whom were false-positives. There is a tendency for the misclassified respondents to suffer from chronic physical ailments, and to be older. The GHQ-30 appears not to have high specificity (65%) and sensitivity (73%). The predictive value (53.3%) of a positive finding by this screening instrument in this population is also low. Informed consent was obtained from participating subjects.

Adult↗

Syndromes of epilepsy in childhood and adolescence.

This report concerns the more commonly recognized epileptic syndromes that have their onset or entire clinical course in childhood and/or adolescence. It hopes to demonstrate the close relationship between the classifications of epileptic syndromes. It will also discuss how knowledge of the epileptic syndromes will enhance the management plan for the patient with epilepsy.

Adolescent↗

Seizures induced by exercise.

Three patients had a clinical history of epileptic seizures during exercise. In all three patients, generalized epileptiform EEG abnormalities were activated by exercise, whereas none had paroxysms during resting wakefulness or during hyperventilation, and only one had a paroxysmal discharge during sleep. Advice to epileptic patients about physical activity should be based on a careful history of individual tolerance. In doubtful cases, an EEG recorded during exercise can provide evidence for an epileptic mechanism.

Adolescent↗

The clinical recognition of subacute tetanus.

The clinical features of a modified form of tetanus, termed 'subacute tetanus', occurring in non-immune patients are presented as manifested in five patients. Subacute tetanus has a good prognosis and favourable outcome. Trismus and abdominal rigidity may be minimal or absent. Nocturnal, brief generalized muscle spasms, palpably contracted sternomastoid muscles and spastic limbs are common features of the disease. The pathophysiology of the nocturnal muscle spasms requires elucidation.

Adult↗