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A O'Brien

Publications and source records attributed to A O'Brien.

54 records · Page 3Linked to original sources
PubMed1982

Correlation of the Bruininks-Oseretsky Test of Motor Proficiency with the Southern California Sensory Integration Tests.

Correlations between the Bruininks-Oseretsky Test of Motor Proficiency (BOTMP) and the Southern California Sensory Integration Tests (SCSIT) were studied by using test results obtained from a sample of 49 learning-disabled children. It was found that those SCSIT tests with a motor component correlated significantly with the BOTMP battery composite scores. The fine motor composite scores of the BOTMP reflected the greatest percentage of significant correlation with SCSIT tests. These results suggested that the BOTMP would be useful for screening children for referral to occupational therapy by educators. In addition, the high correlation of the BOTMP with the SCSIT motor tests indicated that the BOTMP may be appropriate for use in clinical research to evaluate the effectiveness of sensory integrative procedures in relation to motor function.

Child↗
PubMedDate not supplied

Multisystem complications of bulimia: a critical care case.

Bulimia is an eating disorder characterized by behaviors which can lead to very serious health problems. Behaviors such as binging and purging and abuse of emetics, diuretics, or laxatives can cause serious complications, sometimes of a critical nature. Nurses must maintain a high index of suspicion for this disorder and use skillful assessment and intervention to prevent the critical multisystem complications of bulimia.

Adult↗
PubMedDate not supplied

A guide to competency-based orientation. Develop your own program.

Nursing orientation should provide the requisite knowledge and skills to enable a nurse to perform competently in a new work environment. This article provides a step-by-step guide to the development of a competency-based orientation program that is supported by well-developed preceptors. It is written in a "how-to" format, providing the guidance and tools necessary for a nurse educator to develop a program that is institution specific.

Clinical Competence↗
PubMedDate not supplied

Induction of c-myc oncoprotein and of cellular proliferation by radiation in normal human urothelial cultures.

Normal urothelial cultures were established from transplant ureters and irradiated or exposed to nitrosamines. The cells which survived the treatment were monitored for expression of c-myc oncoprotein. The cultures were also exposed to tritiated thymidine (3HTdR) to determine the total number of cells synthesizing DNA. The area of explant outgrowth was also measured. Proliferation is considered to be a fundamental precondition which has to be present before malignant change can take place or which has to accompany this change. The results indicate that the overall growth rate of the carcinogen-treated cultures is relatively faster than that of the controls. This is particularly true one to two weeks after carcinogen exposure. Certain areas of the culture develop abnormally, cells are different in size and shape to the normal uroepithelial cell and have the capacity to pile up and form characteristic foci. These foci continue to proliferate after senescence of control cultures and after senescence of normal areas of treated cultures. The cells in these foci express high levels of c-Myc oncoprotein. Control and treated but normal cells are negative for this antigen under the conditions used. N-ethyl nitrosamine (NEN) (0.005-0.05 micrograms/ml) and radiation (2.5-10.0 Gy) are both able to induce the changes described. The results suggest that radiation and/or nitrosamine treatment can induce uroepithelial cells to divide at a faster rate than usual. Certain cells within this fast growing culture attain the capacity to pile up and acquire a different morphology. These cells do not senescence at the usual time and are c-myc positive. They may represent a subpopulation which has undergone some pre or early malignant changes.

Cell Division↗
PubMedDate not supplied

Diabetes mellitus in an adult cystic fibrosis population.

Medical records of 132 patients attending an adult cystic fibrosis (CF) clinic were analysed to define the prevalence and clinical significance of diabetes mellitus (DM) in CF. Eighty four (63.6%) had normal blood glucose levels, 30 (22.8%) had hyperglycaemia only during intercurrent illness and 18 (13.6%) had DM. No significant differences were noted between the diabetic and non-diabetic groups for age, gender, height, weight, body mass index (BMI), forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) and pancreatic supplementation. Patients with hyperglycaemia during intercurrent illness had significantly lower BMI, FEV1% and FVC% than those with normal blood glucose levels. Of the diabetics four were managed on diet, three received oral hypoglycaemic agents and eleven were insulin requiring. The prevalence of DM in CF is considerable, severity of CF does not correlate with development of overt DM, and CF patients should be screened for DM by an oral glucose tolerance test on reaching adulthood.

Adult↗
PubMedDate not supplied

Diabetes mellitus in an adult cystic fibrosis population.

Medical records of 132 patients attending an adult cystic fibrosis (CF) clinic were analysed to define the prevalence and clinical significance of diabetes mellitus (DM) in CF. Eighty four (63.6%) had normal blood glucose levels, 30 (22.8%) had hyperglycaemia only during intercurrent illness and 18 (13.6%) had DM. No significant differences were noted between the diabetic and non-diabetic groups for age, gender, height, weight, body mass index (BMI), forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) and pancreatic supplementation. Patients with hyperglycaemia during intercurrent illness had significantly lower BMI, FEV1% and FVC% than those with normal blood glucose levels. Of the diabetics four were managed on diet, three received oral hypoglycaemic agents and eleven were insulin requiring. The prevalence of DM in CF is considerable, severity of CF does not correlate with development of overt DM, and CF patients should be screened for DM by an oral glucose tolerance test on reaching adulthood.

Adult↗