[Differences between primary and specialist care in the presentation and evolution of patients with high digestive haemorrhage due to peptic ulcer].
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Biomedical subjects
Publications and source records attributed to A Obrador Adrover.
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AIM: To construct a model to enable calculation of rebleeding risk in patients admitted to a hospital emergency department with upper gastrointestinal bleeding secondary to a gastric or duodenal ulcer. METHODS: We analyzed 317 patients admitted during a 13-month period with an episode of upper gastrointestinal bleeding secondary to a gastroduodenal ulcer. The patients were followed-up for 30 days after discharge. Uni- and multivariate analysis of the clinical and endoscopic variables was performed on variables that could be associated with an increased risk of rebleeding. RESULTS: In the univariate analysis the following variables were significantly associated with an increased risk of rebleeding: the presence of blood in the endoscopically examined tract (p < 0.0001), clean ulcer base (p < 0.0001), low blood flow (p < 0.047) and size of the ulcer > 2 cm (p < 0.004). Independent risk variables identified by multivariate logistic regression analysis were low cardiac output, the presence of blood in the endoscopically examined tract, size of the ulcer, and type of ulcer base. CONCLUSION: Patients with a clean ulcer base, smaller than 2 cm, without blood in the endoscopically examined tract and with stable hemodynamics were at very low risk of rebleeding and could be discharged directly from the emergency room.
We present a case of non-Hodgkin's lymphoma of B cells in a patient with cirrhosis by hepatitis C virus. Our patient presented scarce symptomatology related with non-Hodgkin's lymphoma. A notable hyperbilirrubinaemia with hypoalbuminaemia were the only features that allowed us to suspect the diagnosis. The diagnostic was proved by necroscopic study. There are several factors involved in the etiology of non-Hodgkin's lymphoma, including infectious agents. Recent Italian studies have suggested an association between C virus infection and non-Hodgkin's lymphoma. We have carried out a bibliographical revision of this association to conclude that important geographical differencies must be pointed out.
Acute hemorrhage from pancreatic pseudoaneurysm is the most rapidly fatal complication of pancreatitis, with a reported mortality rate of > 90% in untreated patients. The diagnosis of pancreatic pseudoaneurysm requires a high index of suspicion and the abdominal angiography is the gold standard. Transcatheter embolization is an alternative to surgery for treatment in selected patients. Early diagnosis and treatment decrease the mortality dramatically. We describe a patient with a gastrointestinal bleeding from a ruptured pancreatic pseudoaneurysm, with an angiography diagnosis and transcatheter embolization. We treated the pseudocyst with an endoscopic drainage. A review of literature is presented.
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An uncommon association of scleroderma and Rendu-Osler disease in the same patient is reported. The authors have not found similar descriptions after an extense bibliographic review. A possible relationship is suggested on the basis of the etiopathogenesis of both disorders; Rendu-Osler syndrome is an hereditary disease of unknown etiology with mesoblastic involvement (embryonic tissue which gives origin to the connective tissue), and scleroderma is an immune disease characterized by diffuse sclerosis of the connective tissue. Rendu-Osler disease was diagnosed because of the presence of angiomatous telangiectasias since childhood, recurrent mucosal hemorrhages, and the possible existence of the syndrome in a familial member. The diagnosis of scleroderma was supported by the demonstration of: 1) cutaneous infiltration, 2) Raynaud's phenomenon, 3) functional esophageal alterations with clinical dysphagia, 4) resorption of the distal phalanges, and 5) conclusive skin biopsy.
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We assessed the quality and completeness of the information of death certificates (CMD) for cancer in Mallorca during 1989. Likewise we studied the possible bias introduced by the excluded cases for lack of clinical information (DCO cases). We compared the information of the death certificates with the clinical records and data of the Population-based Cancer Registry. A global concordance of 77.2% was obtained out of 1,173 certificates. This concordance varied according to sex (males: 79.8%, women: 73.1%; p < 0.01), place of death (hospital: 83.1%, home: 69.6%; p < 0.001) and age ( < 50 years: 77.8%; > 70 years: 74.2%; p < 0.05). The best notified sites were: breast, lung, and leukemias and the worst, unknown and poorly defined sites, bones and soft tissue tumours. We detected that the death certificates carry a subnotification of at least 5% in cancer deaths. Even so, they result a valid source of information for the Population-based Cancer Registry. The cases excluded for lack of clinical documentation present a more advanced age and a greater proportion of hepatic cancers and unknown and poorly defined sites.
Alterations in liver function tests have previously been reported in patients with ovarian disease. We report the case of a woman with prolonged hypertransaminasemia, significant hirsutism and android phenotype who was diagnosed with nonalcoholic steatohepatitis and ovarian stromal hyperplasia.
Abdominal pain is the most frequent symptom of chronic pancreatitis and may, on occasions, lead to great treatment problems. The case of a 35-years-old patient diagnosed with chronic calcifying pancreatitis of enolic etiology who showed dilatation of the main pancreatic duct and intracanalicular lithiasis is reported. Medical, endoscopic and surgical alternatives failed but fragmentation of the lithiasis by extracorporeal lithotripsy was successful.