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A Ochoteco

Publications and source records attributed to A Ochoteco.

At least 19 recordsLinked to original sources
PubMed1994

Local transdermal glyceryl trinitrate has an antiinflammatory action on thrombophlebitis induced by sclerosis of leg varicose veins.

To test the antiinflammatory and analgesic effects of transdermal glyceryl trinitrate (GTN) the authors carried out a double-blind, randomized, controlled clinical study in 21 patients with mild to moderate leg varicose veins who underwent vein sclerotherapy in both legs. GTN or placebo ointment was applied in a blinded protocol along the surface of the sclerosed vein every eight hours until disappearance of inflammation signs. The varicose vein in one leg was treated with GTN and compared with placebo for the vein of the other leg used as control of thrombophlebitis (TP) signs. Fifteen minutes after first application inflammation signs were observed in all cases. The intensity of inflammation signs was assessed as 26% (10.4 +/- 4.1) in GTN-treated veins and as 61.5% (24.6 +/- 6.3) (P < 0.001) in the placebo-treated veins. One hour later only 63% of cases in the GTN group and all cases in the placebo group showed signs of TP (P < 0.001). The reduction in the intensity of signs at this time was 7.7 +/- 3.9 in the GTN group and 19.7 +/- 6.3 in the placebo group (P < 0.001). All veins in the GTN group were free of signs of TP in less than forty-eight hours. In the placebo group, 45% of veins required more than forty-eight hours for complete disappearance of signs of TP (P < 0.001). The authors conclude that GTN has an antiinflammatory effect in TP induced by sclerotherapy. This action may be related to the nitric oxide released from GTN, through a direct action on the vein and the surrounding inflamed tissue.

Administration, Cutaneous↗
PubMed1993

[Does captopril possess antianginal actions? An evaluation of its effects on myocardial ischemia by stress tests in patients with stable angina and normal ventricular function].

INTRODUCTION: We have studied the effects of captopril on myocardial ischaemia in normotensive and hypertensive patients with coronary artery disease and stable effort-induced angina. STUDY DESIGN: A maximal treadmill effort test (Bruce modified) was obtained before and after 60 min administration of 25 mg. p.o. of captopril. In a first open pilot essay, 12 patients were studied. In a double-blind randomized, placebo-controlled, without crossover, 20 patients with the same characteristics and methodology were divided in two groups (10 in placebo and 10 in captopril group) and compared in a maximal treadmill effort test. RESULTS: In the pilot essay, the second test don't showed increments in heart rate, systolic and diastolic blood pressure showed a significant reduction at rest (p < 0.01) and at 1 mV ST segment depression (p < 0.01). Captopril increased exercise duration at 1 mV ST segment depression, time to angina and total exercise time (p < 0.01). In double-blind essay, captopril group results were similar to the pilot essay. In comparing results between placebo and captopril groups the most relevant differences were: significant increment in the time to 0.1 mV ST segment depression (p < 0.01), to angor (p < 0.05) and total exercise duration (p < 0.01). Maximal work-load sustained increased significantly with captopril (7.43 +/- 2.1 to 10.34 +/- 1.8 METS) (p < 0.01). CONCLUSIONS: We conclude that captopril used in monotherapy in patients with chronic stable angina, seems to reduce clinical and electric ischemia and to ameliorate maximal exercise duration and work-load.

Adult↗
PubMed1993

[Lipomatous hypertrophy of the interatrial septum simulating an atrial mass in a patient with a pulmonary embolism: its diagnosis by transesophageal echocardiography and percutaneous biopsy].

A case of lipomatous hypertrophy of the interatrial septum in a patient with a history of repeated pulmonary embolism is presented. Thickening of the interatrial septum mimicking the presence of a right atrial mass was evidenced by transthoracic and transesophageal echocardiography. Lipomatous hypertrophy was suspected. The diagnostic was confirmed by echo guided (transesophageal) percutaneous transvenous biopsy. To our knowledge, there is no relationship between lipomatous hypertrophy and pulmonary embolism and in this case, it could be associated with smoking habit and oral contraceptives.

Adult↗
PubMed1991

[Severe disorders of auriculoventricular conduction after aortic valve replacement. A postoperative electrophysiological study in 36 patients and the long-term follow-up].

Cardiac conduction defects (CD) are common in patients with aortic valve diseases. Several studies have suggested that the occurrence of complete heart block at the time of valve replacement is related with preoperative conduction defects and with other factors like calcium deposits, aortic gradient or poor left ventricular function. We evaluated 36 patients undergoing isolated aortic valve replacement in 29 of them, combined mitroaortic in four, isolated mitral valve replacement in two and subvalvular myectomy in one. In all of them an electrophysiologic study was done at the postoperative period. In group 2 (with preoperative CD) patients were older (mean age +/- SEM; 56.57 +/- 8.90) than in group 1 (without CD) (45.64 +/- 14.79) (p less than 0.02). Surgical times were higher in group 1 than in group 2 (p less than 0.01 and p less than 0.005). The site of block was distal to the His bundle in 59% of patients in group 1 and in 47% in group 2 (p-NS). Complete AV block occurred in 70.5% of patients in group 1 while was of 36.8% in group 2 (p less than 0.05). Severity of conduction defects was unrelated with the type of valve disease, aortic valve calcification or gradient or with poor left ventricular function. Preoperative conduction defects were not responsible of more severe postoperative conduction defects. On late follow-up permanent pacemakers were unnecessary in 33% of patients in group 1 and in 75% in group 2 (p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1991

[The double-orifice mitral valve. An evaluation by two-dimensional echocardiography and color echo-Doppler].

Double-orifice mitral valve is an uncommon congenital heart defect. The isolated occurrence of this anomaly is exceptional and, more often, is encountered in association with other congenital cardiac abnormalities. Principal among these are the partial and complete forms of the atrioventricular canal. In this paper, we present two cases of double-orifice mitral valve. Our first case is associated with subaortic stenosis and coarctation of aorta. The second case is an isolated one resembling a severe mitral stenosis. As we know, the diagnosis of this rare anomaly by color-Doppler technique has not been previously reported. We believe this technique provides definite anatomical and functional information about double-orifice mitral valve.

Adolescent↗
PubMed1990

[Mitro-aortic endocarditis caused by Listeria monocytogenes].

A case of Listeria monocytogenes valvular endocarditis is reported. This patient required mitral and aortic valve replacement by Björk-Shiley mechanical prostheses. Patient clinical condition was progressively deteriorated, affecting the left ventricular function, increasing the size of vegetations and the presence of aortic annular abscess. This case represents the 48th reported in the literature and the third in our country. We here comment about the clinical aspects and the treatment of this infrequent entity.

Aortic Valve↗
PubMed1989

[Endocarditis of a natural valve caused by coagulase-negative staphylococci].

Eleven patients with endocarditis of a natural valve due to coagulase-negative staphylococci are reported. Nine had some underlying heart disease. The course was subacute in seven and acute (two weeks or less) in the remaining four. All patients developed complications: heart failure in nine, arterial emboli in eight, atrioventricular conduction disorders in four, development of paravalvular and/or myocardial abscesses in four, and perforation or rupture of valve leaflets in four. Eight patients were cured, seven of them requiring surgical treatment. Three of the isolated coagulase-negative staphylococci strains were methicillin-resistant; two of them caused community-acquired endocarditis. Natural valve endocarditis due to coagulase-negative staphylococci usually has a subacute course with a tendency to develop severe complications. This makes surgical therapy necessary in a sizeable number of patients.

Adult↗
PubMed1989

[Traumatic tricuspid insufficiency].

Isolated tricuspid valve regurgitation is a rare finding after nonpenetrating chest trauma. The clinical course is usually benign and the time of surgery can be delayed for many years. Two-dimensional Doppler echocardiography is an essential procedure in the diagnosis of chordae tendineae or papillary muscle traumatic injury. We present two cases of traumatic tricuspid regurgitation with mild symptoms undiagnosed for sixteen and forty-three years, respectively.

Adult↗
PubMed1985

Mental illness and ischemic heart disease: analysis of psychiatric morbidity.

In this study we analyze from a cardiologic and psychiatric point of view a consecutive sample of 194 patients treated in a cardiology outpatient unit. A psychiatric morbidity of 44.8% is found, expressing itself fundamentally as depression and anxiety neurosis. It is observed how the presence of chest pain significantly conditions the appearance of psychiatric disturbance, there being, moreover, a tendency in the same direction with increasing degrees of impairment of cardiac function. Certain personal and sociocultural factors also play a significant role in the development of mental illness in these patients.

Adult↗
PubMed1985

The psychiatric correlates of coronary pathology: validity of the GHQ-60 as a screening instrument.

The 60-item General Health Questionnaire (GHQ) and the Clinical Interview Schedule (CIS) were administered to a consecutive series of 194 patients with established or presumptive coronary heart disease (CHD) attending an out-patient cardiology unit. The GHQ proved to be a valid instrument for the routine screening of this population. The presence of organic anginal pain was associated with high scores on the GHQ, but with a lower specificity and a higher percentage of false positives. This was not found in patients with atypical or non-cardiac chest pain. These findings suggest a need for an upward revision of the cut-off score on the GHQ in patients with organic anginal pain. False negatives were found predominantly among patients with personality disorders, and in those characterized by the longstanding nature of their symptomatology and by higher levels of defensiveness.

Adult↗
PubMed1983

Analysis of the amount of tricuspid valve anular dilatation required to produce functional tricuspid regurgitation.

To determine the critical anular dilatation required for functional tricuspid regurgitation (TR) and the role of systolic anular shortening in the severity of TR, 67 patients in whom right ventriculography had been performed were studied. These patients were classified into group I, control (n = 12), and the group II, patients with rheumatic valvular disease (n = 55). Group II patients were subclassified as follows: IIa, without TR (n = 19); IIb, with mild TR (n = 22); and IIc, with moderate to severe TR (n = 14). The angiographic maximal early systolic and minimal end-systolic diameters were measured. The shortening of the tricuspid anulus was expressed as percent reduction of the maximal diameter. The average maximal diameter (mm/m2) was: group I, 21 +/- 2; group IIa, 24 +/- 2; group IIb, 31 +/- 4; and group IIc, 37 +/- 4. The average minimal diameter (mm/m2) was: group I, 15 +/- 2; group IIa, 18 +/- 2; group IIb, 23 +/- 2; and group IIc, 31 +/- 3. The average percent shortening was: group I, 30 +/- 7%; group IIa, 25 +/- 7%; group IIb, 26 +/- 5%; and group IIc, 15 +/- 3%. The rheumatic patients had a larger maximal diameter than did those in the control group. Anular shortening was reduced only in the group with moderate to severe TR and preserved in the other groups, including those with mild TR. The critical diameter was determined to be between the maximal diameter in the rheumatic patients without TR and the minimal diameter in the patients with moderate to severe TR, or 27 mm/m2. Thus this easily measured parameter can determine the presence and significance of functional TR, adding objectivity to the angiographic diagnosis of TR.

Adolescent↗
PubMed1981

Right ventriculography as a valid method for the diagnosis of tricuspid insufficiency.

The value of right ventriculography in the diagnosis of tricuspid insufficiency (TI) is often questioned because of 1) the high incidence of premature ventricular contractions (PVCs) during injections and 2) interference of the catheter in the valve closure mechanism. In 168 patients a commercially available, not preshaped, balloon-tipped catheter was used for right ventriculography. To avoid the induction of PVCs, the catheter tip was placed in the middle third of the diafragmatic wall of the right ventricle, and the balloon was inflated, becoming trapped by the trabeculae. In this position the catheter's side holes should be located in the inflow chamber. To ensure this correct position, and therefore lack of ectopic beats during angiography, a saline test injection was performed previously in every case. With this technique the incidence of PVCs during ventriculography was only 7.7%. In all but one case, such beats were isolated. The 168 patients were divided into three groups according to their likelihood of experiencing tricuspid interference by the catheter: group 1 included 41 patients with a normal heart or with coronary artery disease. No one from this group had TI. Of group II, 28 patients with right ventricular pressure or volume overload or cardiomyopathy, only 2 had TI, both with a previous clinical diagnosis of regurgitation. Group III contained 99 patients with rheumatic heart disease. Thirty-five of them showed angiographic TI, and 24 of these had this diagnosis confirmed either clinically or at surgery. It is felt that this technique of right ventriculography, with its low incidence of PVCs and slight interference with tricuspid closure, is a valid method for the objective study of the tricuspid valve.

Adolescent↗
PubMed1980

Hemodynamic factors that affect calculated orifice areas in the mitral hancock xenograft valve.

From June 1974 to December 1978, 714 Hancock valves have been placed in 605 patients. One hundred seventy-five patients with a mitral xenograft have been restudied. The results were questionable due to the wide scatter and disparity between the calculated and the theoretical orifice of each valve size. To elucidate these differences, the hemodynamic data of 40 isolated, normal functioning mitral Hancock valves were reviewed. Early, middle and late diastolic mitral valve gradients were measured by planimetry and their corresponding flows were estimated by angiography. The paired data were fitted to exponential functions and specific lines for each Hancock valve size were obtained. By superimposing Gorlin's pressure and flow curves on these lines, the instantaneous effective orifice for each Hancock valve can be determined. We concluded that 1) the Hancock valve effective orifice is flow related and always lower than its theoretical opening; 2) normal function frequently cannot be firmly established by the mean effective area; and 3) the nomogram described may help in determining the time-related variations of a particular valve.

Adult↗