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Biomedical subjects

A Ogunkoya

Publications and source records attributed to A Ogunkoya.

4 recordsLinked to original sources

Rapid oral desensitization to isoniazid and rifampin.

A 45-year-old black woman, sputum positive for acid-fast bacilli, developed hypersensitivity to both isoniazid and rifampin. She was admitted to the hospital and desensitized to both medications using modified penicillin protocols. Skin testing was negative to both drugs. Desensitization to isoniazid was complicated by a drug fever that was controlled by prednisone. The patient was able to maintain once-a-day dosing without incident even with steroid taper. To our knowledge, this is the first reported case of dual isoniazid and rifampin hypersensitivity with rapid oral desensitization.

Desensitization, Immunologic

Temporal arteritis in blacks.

Clinicians should be aware that temporal arteritis in blacks has a clinical presentation similar to that found in the white population. Heightened clinical awareness of the possibility of temporal arteritis in black patients should lead to earlier diagnosis and initiation of immunosuppressive therapy, thus helping prevent the severe sequela of blindness that has been documented in about half of the cases of untreated temporal arteritis.

Aged