The development of synthetic vaccines.
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Biomedical subjects
Publications and source records attributed to A Olson.
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The performance of four phototiming systems was evaluated for use with six different intensifying screens. Phototimer response was studied as a function of patient thickness, kVp, field size, and exposure time. Each system demonstrated a sufficient range of sensitivity to produce acceptable film densities with all screens using an average-sized phantom; three systems produced overexposures of thin phantoms with almost all screens. With each phototimer, the kVp response for most screens was similar, allowing the use of a single kVp-compensating circuit. Exposure times had to be twice the minimum response time to avoid overexposure.
Seven calves born to 7 cows fed Nicotiana glauca during portions of the 1st trimester of gestation were deformed at birth. Deformities increased in severity as the calves aged. At birth, calves typically had arthrogryposis of the forelimbs or curvature of the spine; severity varied among calves. In 4 calves necropsied at about 15 months of age, there was general malpositioning and misalignment of the distal ends of the radius and ulna and the proximal ends of the metacarpal bones. Carpal joints were severely affected, fetlock joints were moderately affected, and pastern joints were slightly affected, with lateral rotation of forelimbs common; severity varied among calves. In 1 of the 4 calves, there was moderate torticollis and scoliosis resulting from wedging of some of the cervical and thoracic vertebrae and abnormal cranial curvature of the left thoracic ribs. Histologic changes were not noticed in muscle, brain, spinal cord, or endocrine organs of the 4 calves.
Thermoluminescent dosimetry was used to study the dose received by 50 consecutive paediatric patients. The average thyroid exposure was 7.7 R and the average gonad exposure 0.35 R. The relative contribution of both fluoroscopy and serial film radiography was calculated and over 70% of the thyroid dose comes from the use of the roll film changer. The significance of high thyroid dose is discussed and it is concluded that serial film changers no longer have a primary role in the study of congenital heart disease.
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