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Biomedical subjects

A Ozünlü

Publications and source records attributed to A Ozünlü.

8 recordsLinked to original sources

Fascioperiosteal flap and neo-osteogenesis in radical mastoidectomy: long-term results.

We performed an analysis of long-term outcomes data on 60 patients with chronic otitis media with cholesteatoma who had undergone a surgical procedure based on an improved radical mastoidectomy and an inferiorly based fascioperiosteal flap. We found that at the 2-, 7-, 10-, and 13-year postoperative followup visits, all mastoid cavities were healthy and reduced in volume. At the final examination, the mean cavity volume was found to be decreased by 39% of the mean volume measured 1 month postoperatively. This reduction in volume is attributable to the neo-osteogenic activity of the flap, which was confirmed by histopathologic and radiologic findings. No recurrences took place.

Cholesteatoma, Middle Ear↗

Patient selection and surgical results in obstructive sleep apnea.

In recent years, therapeutic methods have been effective in the management of snoring and sleep apnea. Successful results have been possible through conservative and surgical approaches when the nature and site of obstruction is ascertained by careful investigation. Sagittal magnetic resonance imaging (MRI) of the upper respiratory tract has been the most valuable diagnostic tool in patients with obstructive sleep apnea. This has made it possible to measure the dimensions and distance of the hard and soft palate and tongue base to the posterior pharyngeal wall. Surgery is only indicated when a site of obstruction can be completely determined. In this study, surgical approaches and results obtained in 50 patients after surgery for sleep apnea are presented. Uvulopalatopharyngoplasty (UPPP) had a higher success rate in patients with obstruction at the level of the soft palate, but this rate decreased when it was associated with hypopharyngeal obstruction or when there was hypopharyngeal obstruction alone. UPPP was found to be beneficial in patients with central apnea. Nasal pathologies also played an important role in sleep apnea. Better results were obtained when UPPP was performed in patients who were young, not obese and an apnea-hypopnea index was below 40. Some unusual pathologies included lingual tonsil hypertrophy in the adult, sublingual dermoid cysts and angioma of soft palate and were found to be the cause of OSA. After surgical excision of these pathologies, apneic periods disappeared.

Adult↗

Laryngeal paraganglioma. A review and report of a single case.

Laryngeal paraganglioma originates in the neural crest cells in the laryngeal paraganglia. Two distinct types may be cited on the basis of clinical features, but biopsy is essential for diagnosis. By light microscopy, the Zellballen pattern appears pathognomonic. The treatment consists of surgical excision. In this article, due to the rareness of the tumour, one case of laryngeal paraganglioma is presented. The general knowledge and the available literature are reviewed. The difficulties in the differential diagnosis are stressed and treatment principles are discussed.

Diagnosis, Differential↗

Lingual tonsil hypertrophy producing obstructive sleep apnea.

The hypertrophy of the lingual tonsil is a rare occurrence in adults. This disorder may cause obstructive sleep apnea (OSA) and also may lead to a life-threatening obstruction of the upper airway. Diagnosis of lingual tonsil hypertrophy in patients with OSA requires a careful examination by advanced technologic methods. The sleep apnea is successfully treated by lingual tonsillectomy, with or without tracheotomy. In this study the case of an adult with OSA caused by lingual tonsil hypertrophy which was treated with lingual tonsillectomy is presented, and the diagnosis and the treatment procedure of such cases are discussed.

Humans↗

Rosai-Dorfman disease involving the nasal septum.

Rosai-Dorfman disease, or sinus histiocytosis with massive lymphadenopathy (SHML), is a benign, self-limited pseudolymphomatous entity with characteristic histologic features. The disease may be atypically present in the absence of detectable nodal involvement. This is a case of nasal septum involvement of Rosai-Dorfman disease without clinically apparent lymphadenopathy.

Adult↗

Undifferentiated carcinoma with lymphoid stroma of the parotid gland.

A rare undifferentiated carcinoma with lymphoid stroma (UCLS) of the parotid gland is described in a white Turkish patient. The raised serum IgG to Epstein-Barr virus capsid antigen suggests a causal relationship between Epstein-Barr virus and this type of salivary gland carcinoma. Some clinical features are briefly reviewed.

Carcinoma↗

Multiple sclerosis: a cause of sudden hearing loss.

Sudden hearing loss is a clinical entity which has numerous aetiologies. In cases where the aetiology is not determined, evaluation and treatment of sudden hearing loss are very difficult. A case of probable multiple sclerosis with sudden hearing loss as the initial symptom is reported. The pure-tone audiometry showed a quasi-total sensorineural hearing loss in the left ear; the left side displayed only wave I in the auditory brainstem response (ABR). Electronystagmographic examination revealed hypometric dysmetria and saccadic pursuit abnormalities. Magnetic resonance imaging (MRI) showed high-intensity lesions with multiple foci. After steroid therapy, the patient's hearing loss, vertigo and visual problems improved, but the ABR findings remained unchanged. We have decided to present this case because of the interesting ABR finding revealing the presence of wave I and the absence of all other waves after the normalization of the hearing.

Adult↗