Biomedical subjects

A P Fuller

Publications and source records attributed to A P Fuller.

7 recordsLinked to original sources

PubMed1990

Glottic cancer: results of treatment with radiotherapy in air and hyperbaric oxygen.

This paper is a retrospective analysis of 397 patients with glottic cancer, in which 240 patients were treated in air, and 157 patients in a hyperbaric oxygen chamber (HBO). The three principal dose/time schedules in air and HBO are contrasted, and shown to be iso-effective. The local tumour control rates show a significant improvement in favor of HBO: Stage I, 10%; Stage II, 37%; Stage III, 73%. Morbidity rates are explored, and suggest that the increased local control rate is not attained at the cost of an increased morbidity rate. The planning of the treatment, the preparation of the patient, and any subsequent complications are described. Treatment in the HBO chamber in a busy department has been shown to be a safe and routine procedure.

Adult↗

PubMed1986

Assessment of the effect of chemotherapy and radiotherapy on the auditory function of children with cancer.

Forty children with malignant disease underwent full audiological assessment with pure tone audiometry, tympanometry and measurement of brain stem auditory evoked potentials in an attempt to detect auditory dysfunction resulting from treatment. Significant auditory dysfunction was observed in 8 children. Three children with evidence of a conductive or sensorineural deafness on pure tone audiometry had normal brain stem evoked potentials. One child with a high tone hearing loss and 4 children with no detectable hearing loss on audiometry showed significant differences in the interaural interpeak latencies of selected brain stem auditory evoked potentials. In 2 children these abnormalities had resolved on subsequent testing, 2 had evidence of persistent retrocochlear dysfunction and the remaining child died prior to further evaluation. Routine measurement of brain stem auditory evoked potentials is probably not necessary for the majority of children undergoing treatment for cancer, although such measurements are of value when differentiation between cochlear and retrocochlear damage is required.

Acoustic Impedance Tests↗

PubMed1974