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Biomedical subjects

A P Kushelevsky

Publications and source records attributed to A P Kushelevsky.

5 recordsLinked to original sources

[Skin cancer risk of Israeli workers exposed to sunlight].

To assess the number and types of workers occupationally overexposed to sunlight, we interviewed a national sample of 450 employers in occupational categories involving outdoor work and 5000 of their workers. The workers were assigned to 5 overall risk levels, according to combinations of skin sensitivity to ultraviolet radiation (UVR), total weekly hours of outdoor occupational sun-exposure between 0800 and 1400, and percent of skin surface exposed during outdoor work in the summer. Based on this information it was estimated that out of a total of 379,000 Israeli workers in outdoor occupations, 167,000 (44%) are at increased risk for skin cancer (risk levels 1-3) due to occupational exposure to solar UVR. Their estimated lifetime skin cancer risk is 1.5- to 20-fold higher than that of workers at low or minimal risk levels (4-5). The characteristics of those interviewed with regard to occupation, duration of solar exposure, demographic traits, geographic location, degree of risk awareness and protective measures undertaken, provide a data base for effective intervention to reduce the hazards of occupational solar exposure in Israel. We estimate that an appropriate preventive program may reduce skin cancer in Israeli men to half its current rate.

Humans

The bleaching of the bacteriorhodopsin chromophore by ionizing radiation.

The visible chromophore of bacteriorhodopsin, BR(570), undergoes progressive bleaching when subjected to 60CO gamma-irradiation. The low G-value for bleaching confirms that the site of the chromophore is highly protected. Positive and negative circular dichroic (CD) bands associated with the chromosphone undergo concomitant decrease in a manner which is consistent with two independent chromophores rather than exciton coupling between neighbouring chromophoric site.

Bacteriorhodopsins

Ultraviolet measurements at the Dead Sea and at Beersheba.

Comparative ultraviolet (UV) spectral measurements of direct and scattered sunlight, between 300 and 400 nm, reaching the Dead Sea and Beersheba were made. It was found that the sunlight reaching Beersheba is at least twice as high in UV content as that reaching the Dead Sea. The UV content of the sunlight reaching the Dead Sea in the erythemal band (290 to 330 nm) is particularly low. The implications for heliotherapy are discussed.

Health Resorts