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Biomedical subjects

A P Kutsemilova

Publications and source records attributed to A P Kutsemilova.

At least 19 recordsLinked to original sources
PubMed1994

[The characteristics of the present-day clinical course of tuberculous meningitis].

Clinical patterns of tuberculous meningitis have been analyzed for 32 admissions to the bacterial meningitis department of the 2nd Moscow Infection Hospital in 1983-1991. Early diagnosis of tuberculous meningitis caused great difficulties because of rare cases of tuberculous history, atypical symptoms (an acute onset, in particular), an obscure meningeal syndrome, rare neurological symptoms, atypical liquor characteristics (frequent neutrophil pleocytosis, a small protein rise, normal glucose). Secondary bacterial meningitides presented most serious difficulties for differential diagnosis. So did cerebral abscesses and viral meningitis. Antituberculous therapy should be started at first sings of tuberculous nature of meningitis as the disease outcomes are determined to a large extent by early administration of proper treatment.

Adolescent↗
PubMed1984

[Status of serotonin metabolism in the central nervous system in purulent meningitis and meningoencephalitis].

The authors studied the concentrations of tryptophan, serotonin and 5-hydroxyindole acetic acid in both blood plasma and cerebrospinal fluid of patients with suppurative meningitides and meningoencephalitides of varying severity. The data obtained point to the intensification of serotonin metabolism in the central nervous system at the height of the disease development which may lead to alterations in the functional activity of serotoninergic neurones.

Adolescent↗
PubMed1978

[Functional state of the sympathetic-adrenal system in meningococcal infections].

A study of the functional state of the sympathico-adrenal system by determining the diurnal urine excretion of catecholamines and DOPA was conducted in 29 patients with meningoencephalitis of a meningococcal etiology. These studies demonstrated a significant activation of its adrenal link and a tendency to an increase of activity in the sympathical link with a drop of the reserve possibilities. These changes were most distinctly expressed in cases with prevalent localization of the pathological process in the deep brain structures. These facts made it possible to conclude that there is a lesion in the link of a control of the sympathico-adrenal system. These data were confirmed by results of a study in 18 patients with meningococcal infections by physiological loadings with insulin and adrenalin and a study of the catecholamines and DOPA in the urine portions, which exert specific influence on the state of activity of the sympathico-adrenal system through the hypothalamus and reticular formation.

Adolescent↗
PubMed1976

[Neurological sequelae of the generalized forms of meningococcal infection in adults (a catamnestic study of patients who suffered the disease during 1971--1974)].

The authors conducted a follow-up examination of 118 patients who had meningocaccial meningoencephalitis and meningitis in 1971--1974. Besides a neurological examination the authors performed psychological and EEG studies. It was established that the main expressions of the meningococcial infection during the first 2--3 months following the acute period (and in separate cases up to 1 year and more) were: asthenical syndromes of a different degree, diffuse focal symptoms, neuritis of the cranial nerves, distrubed mental activity and changes in the EEG. For these reasons the estimation of the period of restored working capacity after generalized forms of meningococcical infections should always be strictly individual.

Adolescent↗