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Biomedical subjects

A P McCormack

Publications and source records attributed to A P McCormack.

5 recordsLinked to original sources

Biomechanics of procedures used in adult flatfoot deformity.

A flatfoot deformity can occur secondary to fairly obvious causes, or more subtle and less definable entities. Complicating the situation further, it is likely that the cause of an acquired flatfoot deformity in an adult is multifactorial. This likelihood makes the definition, diagnosis, and appropriate treatment of this condition a daunting task. More research is needed to define further the biomechanics of the foot and to understand the significance of the forces that combine to create flatfoot deformity.

Adult↗

Two reconstructive techniques for flatfoot deformity comparing contact characteristics of the hindfoot joints.

The effect of two different methods of reconstruction of flatfoot deformity and the role of the posterior tibial tendon on the contact characteristics of the hindfoot joints were quantified using pressure-sensitive film. Each of 10 cadaver feet was loaded quasi-statically by an axial compressive force to simulate varying loads. First, a specimen was tested intact, then it was tested after sectioning the spring ligament and loading the specimen cyclically to create one type of flatfoot deformity. It was then tested again after reconstructing the deformity. Reconstructions used were the Dillwyn-Evans procedure (bone graft in osteotomy of the calcaneus) or the calcaneocuboid distraction arthrodesis (CCDA). We found that surgically produced flatfoot deformity altered mainly the talonavicular joint, by decreasing its contact area. The Dillwyn-Evans method had less effect on the talonavicular joint (altering 2 of 6 measured parameters) than the CCDA (3 of 6) and more effect on the anteriomedial facet (altering 3 of 6 parameters) than the CCDA (1 of 6). The Dillwyn-Evans method had more effect on the posterior facet (altering 2 of 6 measured parameters) than the CCDA (1 of 6). Function of the posterior tibial tendon had no effect on contact characteristics of the hindfoot joints after either type of reconstruction. These findings are based on measurements using a quasi-statically-loaded foot model at three selected positions, and results may be different with dynamic loading.

Aged↗

Support of the talus: a biomechanical investigation of the contributions of the talonavicular and talocalcaneal joints, and the superomedial calcaneonavicular ligament.

The goal of this study was to determine the magnitude of force transmission to the talus by its inferior articulations to provide insight into mechanisms involving acquired deformities of the hindfoot. Cadaver feet were mounted in a loading apparatus that applied axial force through the tibia and fibula as well as tensile loading of the tendons of extrinsic musculature. This also permitted positioning of the tibia in the sagittal plane. Eighteen specimens were tested in three selected positions of the gait cycle. In one series, pressure-sensitive film was inserted into the posterior and anteromedial facets of the talocalcaneal joint as well as into the talonavicular joint. In a second series, film was inserted between the talar head and the superomedial calcaneonavicular ligament. In stance position, the specimens were also tested without posterior tibial tendon (PTT) tension. Contact areas and force transmitted across the articulations were greatest in near toe-off position, in the posterior facet of the talocalcaneal joint. The talonavicular joint, the anteromedial facet of the talocalcaneal joint, and the calcaneonavicular ligament articulation showed sequentially decreasing amounts of contact area and force transmission. Mean pressures were similar across all articulations, except in the posterior facet in near toe-off position. From heel-strike to stance, to near toe-off, a trend to increasing contact area and force was noted. No difference in contact characteristics was found in the calcaneonavicular ligament articulation after PTT release. The contact force of the calcaneonavicular ligament against the talus was found to be much smaller than those of other talar articulations; however, its medially oriented direction must contribute to stabilization of the head of the talus against medial displacement. Loss of PTT tension was not found to alter the contact forces acting at the talar head in this model, which might indicate that it shares its talar stabilizing function with other structures.

Aged↗

Effect of controlled local release of sodium fluoride on bone formation: filling a defect in the proximal femoral cortex.

To assess the effect of sodium fluoride (NaF) in the healing of a defect in cortical bone, an experimental model was created by the drilling of 5.0 mm holes in the proximal ends of both femora of 12 adult male New Zealand White rabbits. An interlocking intramedullary implant constructed of poly(d,l-lactic acid) containing NaF was placed in the right femur and an identical implant without NaF (sham), in the left. The implant in the right femur was designed to release NaF in a controlled manner over the duration of the experiment. Ten weeks after implantation, the specimens were removed and were tested in torsion. The mechanical properties were not significantly different between the groups. The femora exposed to NaF had an 18.6% increase in intact cortex near the defect (p = 0.023), however, the deposition of mineralized bone within the defect was not significantly greater. In fact, healing appeared to be impaired by the presence of NaF. There was complete closure of the defect in all but one of the femora with a sham implant, but the tissue had not yet calcified. In contrast, only one femoral defect exposed to NaF had closed. Examination of the material filling the defects of the femora exposed to NaF showed that it was predominantly uncalcified osteogenic mesenchymal tissue.

Animals↗

Disagreeable physical characteristics affecting bystander CPR.

We determined the frequency of certain disagreeable physical characteristics (presence of vomitus, dentures, blood and/or alcohol on the breath) of a cardiac arrest patient and the effect these characteristics have on a bystander's willingness to perform CPR. Data were collected prospectively on 121 nontraumatic cardiac arrest patients, of whom 35 received bystander-initiated CPR involving a total of 42 bystanders. Seventy-one (59%) patients had one or more disagreeable characteristics identified. Forty (33%) patients vomited; 39 (33%) wore dentures; five (4%) had alcohol on their breath; and nine (7%) had visible blood. Of the 42 bystanders involved, 14 were exposed to one or more of the disagreeable characteristics. No bystander interviewed indicated hesitancy in performing CPR when encountering disagreeable characteristics. Seven bystanders stated they felt inadequately prepared to handle patients who vomited. Because of the high incidence of disagreeable characteristics, notably vomitus, in patients suffering a cardiac arrest, specific training in handling such characteristics seems justified.

Adult↗