Biomedical subjects

A P Stamatiadis

Publications and source records attributed to A P Stamatiadis.

5 recordsLinked to original sources

PubMed1992

Combination of serum carcino-embryonic antigen and C-reactive protein--a useful test in preoperative staging of colorectal cancer.

The value of the simultaneous estimation of serum carcino-embryonic antigen (CEA) and C-reactive protein (CRP) concentrations in staging patients with colorectal neoplasias was evaluated. The study included 95 patients with benign or malignant epithelial tumors of colon and rectum. The simultaneous negative values of CEA and CRP were able to exclude stage D tumors with a specificity of 92.6% (P less than 0.001). Simultaneously positive values of CEA and CRP were able to diagnose stage C or D tumors with a specificity of 92.1% (P less than 0.001). It is concluded that the combination of CEA and CRP tests can substantially contribute to the preoperative staging and assessment of the extent of colorectal cancer.

Adenocarcinoma↗

PubMed1990

Value of serum acute-phase reactant proteins and carcinoembryonic antigen in the preoperative staging of colorectal cancer. A multivariate analysis.

In 55 patients with benign or malignant neoplasias of the large bowel, serum carcinoembryonic antigen (CEA), C-reactive protein (CRP), alpha 1-antitrypsin (AAT), alpha 1-acid glycoprotein (AAG) levels, and the percentage of serum protein electrophoretic components were measured. Statistical analysis showed significant correlations between serum CEA, CRP, AAG, and AAT levels and the percentage of serum beta-globulins with the stage of the disease. Multivariate discriminant analysis gave a final prognostic model that included serum CEA, CRP, and AAT levels and the percentage of the serum beta-globulins with a significance of P less than 0.000001. The authors conclude that the serum acute-phase protein levels, in combination with serum CEA concentrations, have a definite role in the preoperative staging of large bowel cancer.

Acute-Phase Proteins↗

PubMed1990

Adenomyoma of the common bile duct.

Adenomyomas are rare pseudotumors of the extrahepatic biliary tract. Their microscopic appearance does not differ significantly from similar malformations of the peritoneal cavity. We describe a patient who presented with obstructive jaundice and who was treated successfully with a surgical resection and a hepaticojejunal anastomosis.

Common Bile Duct Neoplasms↗

PubMed1990

[Changes in free thyroid hormones after epidural anesthesia].

The changes of FT4 and FT3 hormone levels were measured in 14 patients who were submitted to various light operations after epidural anesthesia. The FT3 changes were similar to those usually detected after general anesthesia, a fact that leads to the hypothesis that the afferent stimuli are not the only responsible for the thyroid hormone changes after stress.

Anesthesia, Epidural↗

PubMedDate not supplied

Perforated small bowel diverticulosis. Case report.

Three patients who presented with perforated small bowel diverticulosis were healed by resection of the perforated segment and primary anastomosis. Clinical awareness of this disease may reduce the relatively high mortality reported by most authors.

Adult↗