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Biomedical subjects

A Palojoki

Publications and source records attributed to A Palojoki.

12 recordsLinked to original sources
PubMed1983

Combination chemotherapy in metastatic or recurrent non-small cell bronchogenic carcinoma. 5-year results.

A controlled clinical trial was performed to test two different chemotherapy regimens (doxorubicin + cyclophosphamide + vincristine versus CCNU + vincristine) in 100 patients with metastatic or recurrent non-small cell bronchogenic carcinoma. There was no significant difference between treatment groups in survival or in response. Only 4 patients had a partial remission and there were no complete responders. Median survival was 7 months and 8 patients lived over two years, one patient is still alive (65 + months). The benefit of combined chemotherapy in non-small cell bronchogenic carcinoma remains minimal.

Adult↗
PubMed1977

Chemotherapy in bronchogenic carcinoma.

The effects of three different chemotherapeutic treatment regimens on the survival of one hundred inoperable lung cancer patients was studied in a randomized clinical trial. Of the patients 36 received cyclophosphamide as a single agent, 31 patients actinomycin D--vincristine combination and 33 patients cyclophosphamide--methotrexate--vincristine combination. Epidermoid carcinoma was the most sensitive to the actinomycin D--vincristine combination, whereas small cell anaplastic carcinoma responded to cyclophosphamide alone, and to the cyclophosphamide--methotrexate--vincristine combination. In spite of shrinkage of the tumour no differences were, however, observed in the survival times of the eifferent groups.

Carcinoma, Bronchogenic↗
PubMedDate not supplied

[Thoracoscopy in the diagnosis of pleural diseases].

Direct diagnostic thoracoscopy under local anesthesia has been done in 122 patients. Compared with blind pleural biopsy and cytology, thoracoscopy proved to be of superior value in malignant pleurisy. Thoracoscopy improved also the possibility of a rapid and correct diagnosis in the tuberculous cases.

Adult↗