Comments on "Multichannel signal processing based on logic averaging".
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Bundle of His↗
Biomedical subjects
A Peper
Publications and source records attributed to A Peper.
EEG measurement during electrical stimulation.
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Electric Stimulation Therapy↗
Separation of His-Purkinje potentials from coinciding atrium signals: removal of the P-wave from the electrocardiogram.
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Atrial Function↗
A mathematical model of the hsp70 regulation in the cell.
A mathematical model of the regulation process of the heat shock protein hsp70 in the cell is presented. The model describes the damaging effect of elevated temperature on proteins; the interaction of free hsp70 with injured proteins and its chaperone role in nascent protein translation; the relation between the amount of free hsp70 and the formation of the activated trimer form of the heat shock factor protein (HSF); the binding of activated HSF with the heat shock elements on the DNA; the transcription of mRNA of hsp70 and the synthesis of hsp70. The reaction of the model to a temporal rise in temperature shows an initial decline and a subsequent sharp rise to an ultimately increased level of free hsp70 in the cell. The response of the model to both a single and two consecutive heat shocks appears to closely resemble experimental data on hsp70 synthesis. This general agreement demonstrates the structure of the model to be sound and suitable as a basis for further modelling the complex tolerance mechanism of the cell.
Cell Survival↗