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Biomedical subjects

A Perrone

Publications and source records attributed to A Perrone.

At least 91 records · Page 5Linked to original sources
PubMed1975

[Clinical use of a new absorbable suture material in general surgery].

Results with a new, completely absorbable synthetic suture material made of polyglycolic acid (Dexon) in abdominal and anorectal surgery are reported. It is considered that this material can usefully be employed in the place of known absorbable materials and, under certain conditions, non-absorbable materials. No complications due to inflammation and mucosa ulceration following transparietal migration of stitches in the sero-serous or seromuscular layer of the intestine were noted. The results obtained when stitches were left in situ in 37 intradermal sutures, on the other hand, were not so satisfactory and some scars were judged cosmetically poor after 6 months. These results are felt to be caused by Dexon's long absorption time. In cases of this kind, therefore, it should only be used in the form of removable, single stitches.

Abdomen↗
PubMedDate not supplied

Synthesis of biphenylyltetrazole derivatives of 1-aminopyrroles as angiotensin II antagonists.

Based on preliminary molecular modelling study, the synthesis of two different classes of biphenylyltetrazole derivatives of 1-aminopyrroles, as potentially active non-peptide angiotensin II (AII) antagonists, is reported. Some NH-Boc protected l-aminopyrroles were deprotected, N-acylated, N-alkylated with 5-[4'-bromomethyl-1,1'-biphenyl-2-yl]-1-triphenylmethyl-1H-tetrazo le, and then detritylated to give the first class of title compounds. Other 1-NH-Boc protected 1,2-diaminopyrroles were regioselectively subjected to the 1-alkylation with 5-[4'-bromomethyl-1,1'-biphenyl-2-yl]-1-triphenylmethyl-1H-tetrazo le, to the acylation of the amino group at 2-position of the pyrrole ring, and then to the detritylation process to yield the second class of title compounds.

Adrenal Cortex↗
PubMedDate not supplied

[Unusual cause of ileal occlusion: a coconut bezoar].

A coconut phytobezoar was detected in the distal ileum of a 4-year-old boy, admitted for suspected appendicitis. While persimmon or citrus fruit ingestion has been previously reported as cause of phytobezoar intestinal occlusion, it is the first time that coconut pulp is described to cause ileal obstruction in children. No predisposing factor as previous gastric surgery or Meckel's diverticulum was present. The bezoar was successfully milked past the ileocecal valve into the right colon.

Bezoars↗
PubMedDate not supplied

[Primary aorto-enteric fistula].

Aorto-enteric fistula, i.e. communication between the aorta and the digestive tract, is a clinical condition that usually appears in patients who have already been submitted to aneurismectomy. Primary fistula, in patients not submitted to surgical treatment, is uncommon. The authors describe a case of primary aorto-enteric fistula which was diagnosed and operated on early, with a favourable outcome. The critical analysis of the authors' experience and the literature data stress that an early diagnosis and suitable therapy can reduce mortality.

Aged↗
PubMedDate not supplied

[A case of human dirofilariasis (D. repens) of the spermatic cord].

A 52 year old man, living in the province of Trapani (Sicily), presented with right hydrocele and slight orchialgia. The patient underwent epididymectomy and resection of T. vaginalis. The "tunica" was involved by a granulomatous process, containing a parasite of genus Dirofilaria (D. repens). Dirofilaria repens is a filarial nematode. Dogs, foxes and cats are the definitive hosts and principal reservoirs of the parasite. In humans the parasite dies before reaching sexual maturity and the result is an inconspicuous granulomatous reaction in the subcutaneous tissue. S. Pampiglione et al. (Cattedra di Parassitologia Veterinaria dell'Università di Bologna-Italy) reported from 1971 more than 30 cases of human Dirofilariasis in Italy, suggesting that the parasite is able to migrate from the inoculation site to other districts (lung, eye etc.). The case is exceptional for the localization of the parasite (never reported) and can contribute to a better knowledge of the disease.

Animals↗
PubMedDate not supplied

[Isolated jejunal rupture after closed thoraco-abdominal trauma].

INTRODUCTION: Short bowel disruption following blunt abdominal trauma is rare and hard to diagnose and to treat. Death rate depends both on timing of surgical procedure and on associated lesions. MATERIAL AND METHODS: We show a case of short bowel isolated lesion following fall from mountain bike, III degree in O.I.S. Classification. Abdominopelvic US and helicoidal CT scan were performed, reveling pneumoperitonaeum due to hollow viscus disruption. Surgical procedure was performed within five hours from trauma. RESULTS: No complications occurred in postoperative period. Upper alimentary tract X-ray proved a regular transit, without any fistula. Patient was discharged on 13th day. CONCLUSION: Laparotomy must not be delayed if there is any doubt about bowel conditions: it's demonstrated that timing of surgical procedure is related to prognosis. If haemodynamic status of the patient allows, careful abdomen CT evaluation is mandatory; adequate nutritional support in postoperative period is also very important.

Accidental Falls↗
PubMedDate not supplied

[Renal neoplasms and renal transplantation: current problems and future perspectives].

Primary carcinomas of the kidney can develop in renal transplantation in four sets of circumstances: (1) detected in the donor, (2) detected as a pre-existing neoplasm in the recipient prior to transplantation, (3) as de novo malignancies arising post-transplantation in the native kidneys of the recipient, (4) or in the graft. In Italy, any renal mass detected during harvesting does not allow the use of any organs for transplantation; however, several reports from other countries have already shown the safety and efficacy of transplanting kidneys with small (<4 cm), unifocal, subcapsular tumors, after resecting the lesion at the back table and verifying the negativity of the surgical margins; this strategy could also be evaluated in Italy to expand the donor pool. Acquired cystic kidney disease (ACKD) is commonly observed in uremic patients undergoing chronic hemodialysis (HD); numerous studies have reported an increased prevalence of renal cell carcinoma (RCC) in association with this nephropathy. The use of ultrasound, computerized axial tomography (CAT) and magnetic resonance imaging (MRI) has greatly improved the ability to detect renal tumors at earlier stages associated with ACKD and the morbidity and mortality rate, in either uremic or transplant patients. RCC in the transplanted kidney is rare and, when recognized, requires nephrectomy. However, a conservative approach with nephron sparing surgery has been reported for selected cases as a useful strategy to treat renal carcinoma in the allograft.

Carcinoma, Renal Cell↗
PubMedDate not supplied

[Benign tumors and pseudotumors of temporo-mandibular joint: radiologic aspects].

Benign tumors and tumor-like lesions that involve temporo mandibular joint are very rare. Those more frequent are osteochondroma, chondroma, osteoma, pigmented villonodular synovitis and synovial chondromatosis. The Authors report six cases of patients affected by these pathologies in which imaging, such as TC, MRI and/or ortopantomography have been useful to have a diagnosis.

Adult↗