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Biomedical subjects

A Peterffy

Publications and source records attributed to A Peterffy.

8 recordsLinked to original sources

Open-heart surgery and Jehovah's Witnesses.

The religious community of Jehovah's Witnesses holds that blood transfusion is against God's law. Therefore, surgical treatment of Jehovah's Witnesses is a great challenge for every surgeon, especially for cardiac surgeons because blood transfusion is frequently needed during such operations. In this study we summarize the experience with Jehovah's Witnesses who have undergone open-heart surgery in Debrecen from 1989 to 1999 due to various cardiac diseases. Applying a complex surgical procedure developed by the authors to minimize blood loss during operation, preserved blood products were omitted. Three patients out of twenty-four died during the postoperative period. The twenty-one longtime survivors showed significant improvement in their clinical stage during the mean follow up of 37.6 months. More and more operations are done successfully without blood or preserved blood products worldwide, so it could be said that nowadays surgical treatment of Jehovah's Witnesses has a lower risk than before.

Adult↗

Five-year experience with a suture annuloplasty for mitral valve repair.

We present five years' experience with mitral plication annuloplasty, performed with a semicircular buttressed suture around the posterior leaflet in 130 patients (mean age 58 +/- 11 years) with primary mitral valve disease (n = 71) or functional mitral regurgitation (n = 59). In 65 cases the mitral valve itself was also repaired. Concomitant myocardial revascularization was performed in 40 cases and aortic valve replacement in 43. All but three patients were followed up (97.6%). Postoperative echocardiography showed acceptable mitral area (2.28 +/- 0.39 cm2) and good valve competence in all cases. Inhospital mortality was 3% and late mortality 4.8%. During the follow-up period (22.8 +/- 10.9 months) 8 patients (6.6%) required mitral valve replacement because of progression of native valve disease (n = 4), technical failure (2) or expansion of the annuloplasty suture (2). Mitral annuloplasty thus can be performed simply and with good results, using a strong, non-stretchable buttressed suture. This procedure can be an inexpensive alternative to ring implantation.

Aged↗

Tricuspid and pulmonary valve replacement in carcinoid heart disease: two case reports and a review of the literature.

Valve replacement is the only definitive treatment for patients with carcinoid heart disease. Without valve surgery most of these patients die of progressive right heart failure within one year after the onset of symptoms. The choice of a mechanical versus a biological prosthesis is not clearly defined. We report two cases in whom St. Jude Medical prostheses were used to replace both the tricuspid and pulmonary valves. In one of these patients a concomitant coronary artery bypass operation was performed. This patient is alive 6.5 years after surgery. This is the longest follow up after double valve replacement in carcinoid heart disease.

Bioprosthesis↗

Chylothorax as a complication after delivery.

A 23-year old female who developed a chylothorax as a probable complication after delivery is described and a possible mechanism is proposed. Conservative treatment was unsuccessful and the surgical management was complicated by an anatomical variation with the thoracic duct presenting as a plexiform system instead of a single duct.

Adult↗

Extended intrathoracic resection for lung cancer. Follow-up of 49 cases.

Extended resection was performed for primary lung cancer (stage III) on 49 patients in 1973-1982. Their mean age was 61 (38-76) years. In addition to pneumonectomy (29) or lobectomy (20), surgery included resection of the thoracic wall (8 cases) left atrium (12), pericardium (15), parietal pleura (13) and oesophagus (1 case). Among the 47 "surgical survivors" (96%), the mean survival time was 19.9 +/- SD 20.3 months, and only four patients (9%) were alive after 5 years or more. The cumulative 5-year survival was 14% (4/29 patients). Poorly differentiated tumour forms (squamous cell cancer) carried the worst prognosis, whereas the type of resection and presence or absence of lymph-node metastases did not per se influence survival. The prognosis in extended resection is poorer than in standard lung resection, but superior to that in simple exploration. The surgeon therefore should always be prepared to extend a planned resection when a patient on the operating table is found to have extension of lung cancer to other intrathoracic organs, since only in invasion of the chest wall is the surgical strategy as a rule clear from the outset.

Adenocarcinoma↗

The adjustable half-moon. An alternative device for tricuspid valve annuloplasty.

The adjustable half-moon consists of a flexible braided Dacron tube fitted with two internal Teflon-impregnated sutures. The sutures are anchored at each end of the tube and can be tightened at its centre. Implantation is performed along the annular tissue corresponding to the anterior and posterior tricuspid leaflets. Shortening of the half-moon in unilateral or bilateral fashion can be accomplished after its implantation. Two prosthetic sizes are available, "small" and "large", with a tolerance between 4.5 and 9.0 cm. The device preserves the natural tricuspid valve configuration, avoids the cardiac conduction tissue, permits annular adjustment after completed implantation and provides proper support. Following positive experience in 5 cases with severe functional tricuspid incompetence further use of the adjustable half-moon is advocated.

Aged↗