PubMed HealthSearch

Biomedical subjects

A Petkov

Publications and source records attributed to A Petkov.

At least 19 recordsLinked to original sources

[Incidence of echinococcosis in animals].

Studies were carried out on echinococcosis in animals, making use of the results obtained with investigations carried out throughout this country. A great number of definitive and intermediate hosts were studied. A considerable drop of the percent of infected animals was recorded over the 1966-1984 period both with the definitive and the intermediate hosts. Data is presented on the territorial spread of hydatid echinococcosis. Enumerated are the factors that bear an influence on this process. The demonstration of the high incidence of the disease as well as of the rising number of dogs substantiates the view that the epizootic status is still unfavourable, which is also due to some other factors.

Animals

[Isolation of Escherichia coli O 157 from pigs with diarrhea].

Biochemical and serologic studies were carried out with Escherichia coli strains isolated from pigs affected with diarrhea. A total of 161 were investigated, 13 (8.01 per cent) of which were found to belong to serogroup O 157. Almost all strains proved beta-hemolytic, enterotoxigenic, and K 88-positive. The strains of this serogroup were found for the first time in this country in swine colibacteriosis.

Animals

[Intravital diagnosis of intestinal echinococcosis in dogs under field conditions].

Studies were carried out with regard to the diagnosis of intestinal echinococcosis in dogs as the definitive host when still alive, under field conditions. Effective worming and macrohelminthoscopy in such conditions resulted in 52.36 per cent effect. The value found for the average percent of the overall effect of treatment was close to the real values found for the helminthologic status of intestinal echinococcosis. The method employed minimized the epidemiologic and epizootiologic hazards. It was shown to be economically effective and readily applicable.

Animals

[Case of Pseudomonas aeruginosa infection in tropical snakes].

Microbiologic and morphologic studies were carried out with there tropical snakes (two Boa constrictor and one Pithon molurus) that contracted the disease and died. Pseudomonas aeroginosa was the only organism isolated from the affected portions of the oral cavity and the lung. It was found that all strains of the species isolated were sensitive to gentamycin, tobramycin, and polymixin B. Up to their death two of the animals were treated with tobramycin with no curative effect whatever. The morphologic lesions were confined to the oral cavity, the lung, and the skin only. Histologically, there were necrotic stomatitis and necrotic exudative pneumonia, diffuse fibrinoid degeneration of the connective tissue within all viscera, deposition of fibrinoid in the walls of the myocardial blood vessels, hyaline droplet degeneration of the hepatocytes and the kidney epithelium, and focal infiltrations of pseudoeosinophile leukocytes in the spleen. It is believed that due to the irreversible injuries of the internal parenchymal organs all treatment in the advanced stages of the disease was ineffective even with the use of antibiotics to which the etiologic agent was strongly susceptible.

Abscess

[Phosphatase activity of Pasteurella multocida strains isolated from poultry and mammals].

The qualitative test of Berber et al. was employed to determine the phosphatase activity of Pasteurella multocida strains from birds and mammals (cattle, pigs, and rabbits). Only eight out of a total of 50 Pasteurella strains isolated from birds (34 from cases of acute cholera, 12 - of atypic cholera and 4 - from oedema of the wattles ) proved positive (4 isolated from cases of acute cholera, and 4 isolated from cases of atypic cholera). The remaining 42 strains did not show phosphatase activity. A total of 96 P. multocida strains (37 from cattle, 27 from pigs, and 32 from rabbits) were studied. Positive phosphatase activity were shown to have 32 of the strains isolated from cattle, 26 of those isolated from pigs, and 29 of those from rabbits. In terms of percent 42 (84%) of the investigated strains isolated from birds were negative, and 16% were positive for phosphatase activity. Ninety-six as cited above, were the strains isolated from mammals, of which 90.6% were positive, and 9.4% were negative for phosphatase activity. The phosphatase activity of the Psateurella multocida strains may effectively be used to divide the strains purely biologically - as such isolated from mammals and such isolated from birds. The exceptions observed are likely to be due to migration of Pasteurella organisms from birds to mammals, and vice versa. The phosphatase activity is not shown to correlate with the pathogenicity of the respective strains for albino mice.

Animals

[Method of determining the biochemical behavior of clostridia].

A fast and readily applicable method is suggested for the determination of the biochemical reactions of the spore producing anaerobic organisms. A pepton coloid medium with the addition of 0.15 per cent agar-agar was used as a basic nutrient medium. The cultivation of bacteria did not require any special conditions. Reading of the results was carried out with the addition of 0.1 per cent phenol red after 48 hours of incubation of the cultures. This method showed a number of advantages over the methods used so far.

Anaerobiosis

[Vascular impressions on the renal cavitary system].

The clinical significance of forty vascular impressions confirmed at pyelographies and angiographies and based on clinical material is discussed. The vascular impressions upon the cavity system of the kidney is pointed to lead to urostasis with complications, being the sequelae of it. A scheme of their own is presented by the authors for the morbid disorders ethiopathogenetically conditioned by the vascular impressions on the cavity system of the kidney.

Diuresis

[Allergic reactions in guinea pigs infected with Yersinia enterocolitica type 9 relative to homologous (Yersinia) and heterologous (Brucella) allergens].

Obtained were allergens from Brucella abortus 99 and Yersinia enterocolitica Type 9 through hydrolysis with hydrochloric acid after M. M. Ivanov and with acetic acid after Kirzhaev. They were tested on guinea pigs that were infected with Yersinia enterocolitica Type 9 through different ways. To M. M. Ivanov's allergens all infected animals responded pronouncedly in the case of the homologous allergen, and half of them only and to a lower degree in the case of the heterologous Brucella allergen. To Kirzhaev's allergens the infected guinea pigs showed more strongly expressed skin reactions. In this case, too, the response was stronger to the homologous Yersinai allergen. The diameters of skin swelling were more than twice greater than with the use of the heterologous Brucella allergen, and the sum of the reacting skin sites was five times greater in the case of the homologous Yersinia allergen. No essential differences were observed between the oral and the plantar route of infection combined with the subcutaneous injection of carboneum tetrachloratum and the morphine preparation Omnopon.

Allergens

[Hydrocalyx (Fraley's syndrome)].

Fraley syndrome was observed in 14 cases out of 137 vessel compressions, i.e.--compression of the cranial calix neck, disturbances in urine transport, hydrocalix development with consequent complications. One case with Fraley syndrome is presented and analysis of the clinical progress of the syndrome in ten patients is carried out.

Humans

[Antagonistic action of Pseudomonas aeruginosa in relation to Pasteurella multocida strains].

Studied was the antagonistic action of 4 strains of Pseudomonas aeruginosa toward 48 strains of Pasteurella multocida. Use was made of the method of the delayed antagonism after Fredericq. Ps. aeruginosa organisms were found to manifest a strongly expressed antagonistic activity as regards P. multocida. All Pasteurella strains proved highly sensitive, and showed a zone of inhibited growth sizing from 20 to 70 mm. The antibiotic substance produced by Pseudomonas aeruginosa organisms was yielded better on solid nutrient media than in liquid ones. All Pseudomonas aeruginosa strains manifested bactericidal and not bacteriostatic action upon the studied strains of Pasteurella multocida.

Antibiosis

[Sponge kidney].

Explore the source record for details and available documents.

Adolescent