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Biomedical subjects

A Petz

Publications and source records attributed to A Petz.

4 recordsLinked to original sources
PubMed2004

Mass spectrometric studies on the coupling model reaction towards alkenyl-aryl ketones.

The palladium catalysed coupling reactions of 1-iodo-cyclohexene have been investigated with the aim of the synthesis of model compounds towards unsaturated aryl-alkenyl ketones of practical interest in carbonylative Suzuki reaction. In addition to the target compounds, the formation of 1-aryl-cyclohexene derivatives, 1,1'-bi(cyclohex-1-en-1-yl), 1,2-dicyclohex-1-en-1-yl-ethane-1,2-dione, dicyclohex-1-en-1-yl-ketone and 1-aryl-2-cyclohexenyl-cyclohexene derivatives, as well as their isomerization products, have been observed in parallel and consecutive reactions, respectively. The complex reaction mixtures have been analysed with GC-MS providing valuable information to the investigation of the homogeneous catalytic reaction.

Boronic Acids↗
PubMed1987

Experience with 131I-therapy. Hyperthyroidism in old age.

Retrospective clinical studies of 211 thyreotoxic patients having received 131I-therapy were performed and processed by computer. The patients' mean age was 58 years, the male-female ratio 7.1 to 1. The incidence of symptoms and associated diseases was in agreement with data in the literature. Of the clinical symptoms, weight loss, weakness, fatigability, a fine tremor, decompensation and nervousness, called attention to the condition. Of the ECG changes, an absolute arrhythmia of atrial fibrillation and extrasystole may be indicative of hyperthyroidism. Clinically, there is an essential difference between juvenile and old-age thyrotoxicosis. Differences could also be noted between patients with toxic adenoma and those with non-toxic one. Toxic adenoma patients were more advanced in age and the female-male ratio was higher than in non-toxic cases. Absolute arrhythmia of atrial fibrillation, extrasystole, repolarization disorders, diabetes, hypertension and arteriocardiosclerosis occurred more often, while ophthalmopathy and immune disease were less frequent. The clinical picture may raise the suspicion of old-age thyrotoxicosis. Following laboratory diagnosis, treatment should be administered without delay.

Adult↗
PubMed1982

Thyrotropin and prolactin response to ambient temperature in newborn infants.

Plasma TSH and PRL level was measured by RIA in 8 full-term newborn infants with mean birth weight of 3420 g (range 3000-4100 g) and mean gestational age of 39.0 weeks (range 38-40 weeks) at postnatal age of 3-4 days. Determinations were performed at neutral thermal environment (32 degrees C) and after 1 h exposure to cold (28 degrees C) and warm (37 degrees C) environment. In response to cold challenge, TSH and PRL increased significantly from 4.17 +/- 0.28 mU/1 and 4625 +/- mU/1 to 4.76 +/- 0.21 mU/1 (p less than 0.01) and 5975 +/- 944 mU/1 (p less than 0.05), respectively. When the newborns were placed in warm environment, both TSH and PRL fell significantly to 3.52 +/- 0.4 mU/1 (p less than 0.05) and 3318 +/- 759 mU/1 (p less than 0.05), respectively. A weakly significant positive correlation was found between TSH and PRL levels suggesting that thermal stress in the newborn results in similar alterations in TSH and PRL, presumably through the same central mechanism.

Birth Weight↗