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Biomedical subjects

A Picozzi

Publications and source records attributed to A Picozzi.

At least 19 recordsLinked to original sources

A survey of dentists' drug prescribing practices.

The drug prescribing practices of dentists should be of interest to the dental profession, drug manufacturers, the medical profession and dental educators. This article presents an update on an earlier similar survey reported by the authors as well as information on current infection control procedures, the treatment of hepatitis and AIDS patients, and generic drug substitution. The classes of drugs that are important to the practitioner and the level of prescribing activity have not changed appreciably since the earlier study. There has been, however, a significant change in nonopioid analgesic drug preference with ibuprofen overtaking aspirin and acetaminophen by a wide margin. That age affects the character of practice was confirmed: far fewer older practitioners report prescribing drugs than do their younger counterparts. A very gratifying finding was the high level of compliance with ADA recommendations regarding infectious diseases although fears over treating AIDS patients remain high.

Adult

Soft tissue responses to high frequency use of experimental and commercial mouthwashes.

A recent study reported that regular use of commercial mouthwashes produced a significant incidence of oral reactions, including epithelial peeling, inflammation, ulceration and geographic tongue-like lesions. In view of the widespread use of these preparations, without apparent deleterious effects, an investigation of two commercial preparations (Scope, Listerine) and an experimental mouthwash containing cetyl pyridinium chloride was undertaken to assess the possible irritant effects on the oral soft tissue under stringent test conditions. A double blind design was used and soft tissue effects were measured over a two week period. Rinses were used full strength, 20 cc 3 times daily. Examinations were conducted by an oral pathologist at the start and conclusion of the test period, and a record was made of the occurrence of erythema, hyperemia/prominent vasculature, inflammation, petechia, keratosis, tongue coating, and ulceration. These observations did not reveal any soft tissue conditions beyond those which would be expected in the normal population.

Adolescent

A look at a deviant group of medical school applicants.

A total of 246 physicians who either had graduated from or had matriculated without graduating from dental school prior to entering a medical school were identified, and a combination multiple-choice, open-ended questionnaire was mailed to the group. Completed questionnaires were recived from 194 subjects for a 79 percent response rate. The questionnaire was designed to elicit information about the decision to study dentistry and the subsequent decision to study medicine. The authors were also interested in the process of admission to medical school, in academic performance in both schools, in choice of medical specialty, and in attitudes toward dentistry and medicine.

Achievement

Influence of a chlorhexidine and a zinc mouthrinse on gingivitis.

The end point methodology did not indicate a difference between the agents. The prophylaxis effect was only demonstrable through 8 weeks, although the analysis of variance indicated a prophylaxis effect on gingival index throughout the study. An agent effect was not demonstrable in the study. The "positive control," chlorhexidine, did not give the same results in this brushing study as in previous no-brushing studies reported by Loe and by our group. One might conclude that the effectiveness of brushing in reducing gingivitis is greater than the effect of chlorhexidine. Decreasing plaque and gingivitis scores are seen with increasing time, probably reflecting increased subject interest and involvement in the study. Mere involvement in the study apparently produced a beneficial effect on gingival health. This "placebo effect" also has been noted in an earlier study. A similar decrease in plaque scores in a placebo group attributable to a general improvement of oral hygiene was reported by Gjermo and Rolla. The subjects who began the study with no calculus (prophylaxis group) had consistently lower calculus scores than those not given a prophylaxis. This difference became less distinct at later exams, as the treated group developed calculus. The agents, although ineffective under the test regimen produced no adverse effects.

Biguanides

Mouth protectors.

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