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A Piermattei

Publications and source records attributed to A Piermattei.

60 records · Page 4Linked to original sources

Preoperative radiotherapy and IORT in resectable rectal cancer at high risk for local recurrence.

Over a 4-year period 35 patients with mid- (15 patients) and low (20 patients) rectal cancer clinically staged as T2 N1-2, T3 N0-2 underwent a protocol of combined surgery and radiotherapy. The protocol included: preoperative external beam radiotherapy (38 Gy, ICRU50); surgical resection; IORT on tumor bed (10 Gy). Toxicity of preoperative treatment was mild with a single case (2.9%) of grade 3 gastrointestinal toxicity. 18 patients underwent anterior resection and 17 abdominoperineal resection. Perioperative mortality and morbidity were 0% and 17.1% respectively. At a mean follow-up of 25 months all patients were alive. The single anastomotic recurrence observed was rescued with abdominoperineal resection.

Endoscopy↗

[Determination of computer tomography dose index by means of ion chamber measurements].

The effective dose (ED) and the organ dose given with Computer Tomography (CT) scanners can be determined by means of a computing method suggested by the English National Radiological Protection Board (NRPB). This method uses the integral air-dose profile as input. Due to the non-rectangular shape of the CT profiles, a Computer Tomography Dose Index (CTDI) has been defined, as the integral dose profile divided by nominal slice thickness. The experimental determination of the CTDI can be carried out with thermoluminescent dosimeters. However, the measurement can be simplified by using a cylindrical ion chamber. This paper reports the calibration of a PMO5 ion chamber (5 cm3 in volume and 5 cm in length) in terms of sensitivity value (4.45 pC mGy-1 mm-1). CTDI measurements by means of a PMO5 ion chamber were used to determine the effective doses and lung doses for the CT scanners used at the Institute of Radiology of the Catholic University in Rome. The dose levels thus obtained are in agreement with other national and international data. Moreover, the method allows the differences in the doses absorbed by the patients submitted to CT with different technical approaches to be calculated.

Humans↗

Quality assurance in planning and implementing radiation therapy.

Quality Assurance (QA) programs in radiotherapy are based on an interdisciplinary team work with the participation of physicists and physicians in treatment decision-making and in the determination of accuracy in dosimetry. In this short article, quality control (QC) procedures for computer-assisted treatment planning and implementation, are reported. Particular attention is paid to the technological developments which could make QC programs feasible at Radiotherapy centers.

Humans↗