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Biomedical subjects

A Popovici

Publications and source records attributed to A Popovici.

At least 19 recordsLinked to original sources

A comparative study of processing simulated and experimental data in elastic laser light scattering.

The intensity of the laser light scattered by a suspension of biological particles undergoing Brownian motion contains information about their size distribution function and optical properties. We used several methods (implemented in MathCAD programs), including a new one, to invert the Fredholm integral equation of the first kind, which represents the angular dependence of the elastic scattering of light. The algorithms were first tested on different sets of simulated data. Experimental data were obtained using biological samples and an experimental arrangement which are briefly described. We study the stability of the inversion procedures relative to the noise levels, and compute the first two moments of the retrieved size distribution function. A comparison of the results corresponding to simulated and experimental data is done, to select the best processing algorithm.

Algorithms↗

[Non-operative/conservative treatment of hemoperitoneum in children].

The authors present 34 cases of the traumatic hemoperitoneum with nonoperative/conservative treatment followed up in the past five years. The cases of hemoperitoneum are divided into three categories: hemorrhagic shock; stable clinic status; unstable clinic status. The first category included the cases of operational emergency, the other two categories were treated in the intensive care unit; the most of them needed no operation. The punction and punction-lavage of the peritoneum was systematically carried out and it was a therapeutic step of draining out the blood and appreciating the importance of hemoperitoneum. If laparotomy was requested initially or later on, a conservative surgery was used: spleen-hepatorrhaphy, partial splenectomy, selective arterial ligations, splenic replantation.

Adolescent↗

[Difference between dental plaque formation by Lactobacillus Sp. and Strep. mutans].

Human teeth were suspended in a basal medium with sucrose 10%; they were incudated for formation of dental plaques "in vitro". The microorganisms used were: Strep. mutans, Lactobacillus salivarius var. salivarius and a mixture of them. The following aspects were stablishad by scanning electron microscopy: 1) The teeth inoculated with Strep. mutans had coccoid forms, lying on an organic film with spheric spaces in some sectors, and irreguar forms in others (Fig. 1). 2) The teeth inoculated with Lactobacillus salivarius had rod forms attached to the adamantine surface (Fig. 2, 3). 3) Teeth incubated with the mixutre had rod forms over a granular film (Fig. 4). 4) The control teath did not have plaque (Fig. 5). This experience shows that the extracellular polisacharide, reticulated or granular (mutano) appeared only in teeth incubated with Strep. mutans alone (Fig. 1) or mixed with Lactobacillus (Fig. 4). On the other hand Lactobacillus appeared attached on the enamel surfaces, perhaps due to cohesive adhesive forces (Fig. 2). Two different interpretation or the formation of dental plaques that take place on the enamel free surfaces of teeth are presented.

Culture Media↗

[41 hepatic resections].

Clinical and therapeutical aspects are discussed with reference to 41 cases of malignant and benign tumours of the liver for which various types of hepatic resections were performed. The high mortality rate (22%) and short postoperative survival (less than a year) in malignant tumours of the liver plead for limited hepatic exeresis in cancer. Hepatic exeresis in benign tumoural pathology gave better, but nevertheless restricted, immediate and late results. Hepatic scintigraphy with colloidal 198Au and 131I rose bengal proved to be useful both preoperatively for determining the quality and quantity of the intact hepatic parenchyma and for late, postoperative follow up of the hepatic regeneration process. Moderate intraoperative hypothermia was used as an adjuvant method, allowing for the approach of broader hepatic exeresis by scissural access and longer clamping of the hepatic pedicles and inferior vena cava.

Actinomycosis↗

[Palliative total gastrectomy in advanced malignancies of the stomach].

The diagnosis of the malignancies of the stomach is generally late (stages III and IV to a medium value of 80% of patients). Therefore it is necessary a surgical treatment in order to effectuate the extirpation of the lesions and to warn or to treat the complications in course of the neoplastic disease. The indications and the results of the palliative total gastrectomy (PTG) are analyzed in the present study. Between 1992 and 1999 there were studied retrospectively and prospectively during three successive periods of time, 217 patients (pts.) with PTG. This group of pts. represents 22.1% of the total number of pts. operated on for gastric malignancies (carcinoma particularly). The indication of PTG was established only after one complex evaluation of the every patient from the point of view of his general and biological status. 142 (65.4%/217) of the analyzed pts. presented at the admission in the hospital various complications of the malignant disease (gastric different stenosis, digestive hemorrhages, loco-regional invasion). The lymph nodes metastases and the systemic metastases (in the liver especially) as well as the invasion in the neighbouring viscera imposed sometimes the extension of the PTG with partial or total extirpation of the invaded organs. A proportion of 61% pts. were submitted to those type of enlarged surgical interventions without radical intentions; all the operated pts. remained by necessity in R1 or R2 types of operations. The reconstructive preferred anastomosis was effectuated with an Y jejunal ansa à la Roux completed or not by a "J" reservoir. Microscopically pathologic lesions were: adenocarcinoma and carcinoma (82%), followed by primitive lymphoma (11.5%), and others malignant forms of lesions (approximately 6%). The general perioperative morbidity was 32.5% divided in: 12.3% having a surgical cause (the majority anastomotic leakages +/- septically complications or precocious occlusions); 20.2% complications depending by the general status and altered biology of the patients. Perioperative mortality was 10.1% (22 pts.) comparable with other experiences published in the international literature in those forms of advanced gastric cancer operated by PTG. The average outcome of the operated followed pts. was 16-18 month (extremes 12 months and 29 months). A better quality of life and a variable disease-free period was obtained. As a conclusion we think that the PTG is a advantageous modality of surgical treatment with an acceptable rate of perioperative morbidity and mortality. The outcome of operated pts. is superior comparable with that of nonoperated pts. or with that secondary to other palliative surgical interventions. The importance of adjuvant treatment (chimeo- or radiotherapy) remain to be appreciated in the future.

Adenocarcinoma↗