PubMed Health⌕ Search

Biomedical subjects

A Pradhan

Publications and source records attributed to A Pradhan.

27 records · Page 2Linked to original sources

Metabolism of some drugs by intestinal lactobacilli and their toxicological considerations.

The bacterial metabolism of three drugs (sulphasalazine, phthalylsulphathiazole and chloramphenicol palmitate) and two dyes (tartrazine and methyl red) has been studied using a resting culture technique. The strains used were isolated intestinal lactobacilli, E. coli and mixed cultures of faeces of mice. As high as 94.3% degradation of sulphasalazine was found with a strain of Lactobacillus acidophilus. The highest degradation of phthalylsulphathiazole and chloramphenicol palmitate was found to be 17.6% and 8%, respectively. A kinetic study was conducted on the rate of degradation of sulphasalazine, phthalylsulphathiazole and methyl red. The toxicological aspects of degradation products in relation to the use of lactobacilli as dietary supplement or therapeutic aid are discussed.

Animals↗

Backache prevalence among groups with long and normal working day.

OBJECTIVES: to describe the prevalence of backache among groups with long and normal working day. DESIGN: A cross sectional study of prevalence of backache among groups with long and normal working day. MATERIAL AND METHOD: Among the 19 wards of Kirtipur municipality, ward no. 11 was selected as a random cluster. 64 households of different socioeconomic status were selected at random. Total of 64 individuals from these households were selected in the study. CONCLUSION: The backache was found to be 62.5% prevalent. 75.8% of individuals in long working day category were found to be suffering from backache whereas 48.4% in normal working day group were suffering from it.

Back Pain↗

Faculty opinion survey following attendance to teacher training workshop in Kathmandu Medical College.

INTRODUCTION: With the growing awareness of the importance of teaching and learning in Universities, the need to improve professional qualities in teachers has been identified. AIM AND OBJECTIVES: This paper describes the outcome of the impact of teacher training workshops on faculty- teaching performance. METHODOLOGY: A total of 30 faculties who had undergone teacher training in the one-year period were included in the study. Survey questionnaire were distributed and all the forms were returned. RESULTS: All (100%) respondents found the teacher training to be very useful/useful for improvement of teaching skills. A total of 76.66% said that the skills learnt in the workshop were very applicable, 80% perceived changes in students classroom behaviour and found their lecture to be more participatory and interactive. As for their own change in behaviour, 66.66% respondents experienced better interaction with the students in classroom. DISCUSSION: The overall impression of the training was very positive. Future studies should include student feed back and classroom teaching observation for faculty teaching evaluation. We also need to utilise the feed back information obtained in this article, to further improve the strength of the future teacher training workshops. The future workshops should include sessions in problem-based learning and follow up refresher courses.

Attitude of Health Personnel↗

HIV/AIDS and STI related knowledge, attitude and practice among high school students in Kathmandu valley.

OBJECTIVE: To assess the knowledge, attitude and practice of high school students regarding HIV/ AIDS and STI and to determine if a school education programme would bring about statistically significant positive change in the knowledge, attitude and practice regarding HIV/AIDS and STI. METHODS: The study was conducted among 1012 students of various schools in Kathmandu Valley (Kathmandu, Bhaktapur and Lalitpur). The tool for assessment was confidentially administered closed questionnaire both before and after the education programme of 45 minutes single class, standardized education package. RESULTS: Knowledge on some aspect of the disease was quite low in the study group. 45.8% had prior knowledge of HIV, 65.2% knew that HIV/AIDS could be transmitted by sharing same needle, 46.2% knew that vaccine is not yet available for HIV/AIDS. Knowledge about STI was also quite low, 41.5% knew that pus in the urine is a symptom of STI and 41.7% knew that STI is curable. 4.2% of the study group had previous sexual intercourse, 64.2% had sexual intercourse with friend and 35.17% had sexual intercourse with commercial sex workers. 1.8% would commit suicide if they contracted HIV/AIDS. According to sex wise distribution of the sample, female's knowledge about HIV was low 43.2% as compared to male 48%, male's knowledge about transmission of HIV/AIDS from pregnant mother to child was low; 89.7% as compared to female's knowledge 94.2%. Female's knowledge about commercial sex worker as high risk group was low (87.8%) as compared to male's knowledge 90.6%.

Adolescent↗