PubMed Health⌕ Search

Biomedical subjects

A Ptok

Publications and source records attributed to A Ptok.

17 recordsLinked to original sources
PubMed1994

[Drug therapy of acute inner ear hearing loss in childhood and adolescence].

Sensorineural hearing loss in early childhood may severely interfere with normal speech and language development. This by itself requires pursuit of an effective therapeutic procedure. Here we report the results of therapy with a rheological agent and procaine-HCl with or without the addition of steroids. Immunological testing was also studied for possible circulating antibodies in sera of affected children. Retrospective analysis of therapeutic results showed that the therapeutic procedure employed may be beneficial, since hearing improved considerably in some cases. Since an autoimmune-related sensorineural hearing loss has been postulated for some years, results presented here could be used as an argument for the presence of antibody-related inner ear disorders in early childhood. These findings suggest that circulating antibodies in children suffering from sensorineural hearing losses produce an inflammatory process involving inner ear structures. Circulating antibodies may also indicate a secondary immune reaction. However, sensory hearing loss occurring in early childhood may be steroid sensitive.

Adolescent↗
PubMed1994

[Functional screening evaluation of hearing aids].

A complaint about a malfunctioning hearing aid (HA) usually will require thorough testing of all aspects of hearing aid functions by the hearing aid dispenser. However, ENT physicians can also detect defects easily by following the simple screening procedure described here. Before testing the HA function, the following questions should be answered: Are the body of the hearing aid and ear mold intact? Is the ear canal free of irritation and is the acoustic isolation of the ear canal by the HA sufficient? A rough estimate of HA function can be accomplished by covering the HA with the hand. If the HA is switched on, a feedback, high-pitched sound should be produced. HA amplification can be assessed by using a stethoclip. After the examination is completed, all switches should be put back into their previous positions. Although these basic procedures are not equivalent to diligent and comprehensive acoustical testing, they are still useful for the otologist to detect major faults in the HA before referring the patient to the hearing aid dispenser.

Adolescent↗
PubMed1993

Orocaecal transit time in patients with Crohn disease.

Orocaecal transit time (OCTT) using the lactulose hydrogen breath test was investigated in 16 patients (age 10-19.4 years) with active Crohn disease (CD). Disease activity was assessed by the paediatric CD activity index (PCDAI). OCTT was prolonged in all patients (mean 149.9 min, SD 32.7) relative to healthy age-matched controls (mean 56.9 min, SD 11.1). PCDAI was increased (median 48.8, range 32.5), indicating moderate to severe disease in all patients. A close correlation between OCTT and PCDAI (Spearman r = 0.90) was observed. Following nutritional therapy with a semi-elemental diet over a period of 6 weeks OCTT and PCDAI declined, OCTT becoming normal in 4 and PCDAI in 4/12 patients respectively. OCTT provides a sensitive, non-invasive method for the assessment and followup investigations in patients with CD.

Adolescent↗
PubMed1993

[Spectral analysis of sounds produced by musical instruments and other sounding bodies for hearing screening of children].

Some time ago audiological screening in infants was mostly performed using musical instruments or equivalents. The use of acoustic evoked potentials and oto-acoustic emissions changed the strategies of hearing assessment in newborns and infants, however, musical instruments are still in use. An adequate interpretation of screening results obtained with musical instruments necessitates a profound knowledge of frequencies and intensities derived from these instruments. In this study spectral analyses of sounds from these instruments were performed. The results may be of value for those using musical instruments as a tool for audiological screening. In addition, the results show that with some instruments intensities able to cause inner ear damage can be generated.

Child↗
PubMed1989

[Current aspects of radiotherapy of glomus jugulare tumors].

Small glomus jugulare tumors can be operated on successfully. The intraoperative risk of bleeding may be reduced by preoperative irradiation or angiographic embolisation. Patients with advanced tumors (bone destruction, paralysis or cranial nerves and/or invasion of brain) are at high risk if they are operated on. In these cases radiotherapy is an effective alternative with a fairly low complication rate. Prerequisites for successful irradiation are assessment of treatment volume and treatment planning by CT, sophisticated stereotactic irradiation techniques, application of high energy photons and reliable immobilisation measures. Furthermore it is possible to deliver higher doses, leading to regression of the tumor and its symptoms. The technique is illustrated by two characteristic cases. Although irradiation alone can achieve tumor remission the long term prognosis remains doubtful.

Female↗
PubMed1989

[Assessment of kidney function before cisplatin administration: the need for 24-hour urine collection].

Creatinine clearance as a measure of the glomerular filtration rate is calculated from the serum creatinine, urine creatinine concentration and the 24-h urine volume (MCC). Cockroft and Gault as well as Davila and Gardener have shown that estimation of the creatinine clearance (ECC) from the serum creatinine, age, sex, and weight of the patient is at least as accurate as measurement of creatinine clearance (MCC). ECC is not influenced by inaccurate collections of urine or incorrect analyses of urine creatinine. 125 MCC was investigated in 51 patients receiving cisplatin. If ECC is less than or equal to 80, then MCC should eliminate inaccurate urine collections. If the value of ECC exceeds 80, it is not necessary to measure MCC.

Circadian Rhythm↗
PubMed1987

[Surgical treatment of the lacrimal apparatus--technics and results].

After a short review of anatomy the clinical and radiological diagnosis of stenoses of the lacrimal duct system are discussed in detail. Microcatheterdacryocystography and high resolution CT are very important in determining the indications for surgery. Microsurgical endonasal dacryocystorhinostomy is preferred for treatment of postsaccal stenoses. It is also the method of choice for one stage definitive therapy of acute lacrimal sac empyema. Surgical reconstruction in cases of presaccal stenoses is difficult and should be handled individually. For intubation of the canaliculi we have developed a special modified pigtail-hollow-probe (Draf-Haag 1981), which reduces damage to the epithelium. If reconstruction of the natural lacrimal duct system is not possible, a conjunctivorhinostomy by Walter's technique is indicated. The different surgical concepts and results are discussed.

Catheters, Indwelling↗
PubMed1986

[Diagnosis and operative sequela of rare abnormalities of the inner ear].

Two cases of congenital unilateral deafness in otherwise normal children are presented. X-ray examination showed a partition of the inner ear canal in one of them. A review of the literature showed this lesion to be very rare, but it is more frequent in combination with other malformations such as the Klippel-Feil-syndrome, Wildervanck-syndrome and Thalidomide embryopathy. The second child showed an extensive malformation of the cochlear and vestibular parts of the inner ear and of the internal auditory meatus. The vestibulocochlear nerve was absent. An arachnoidal cyst protruding into the tympanic cavity formed the only boundary between the middle ear and the cerebrospinal fluid. This resulted in relapsing meningitis and a postmeningitic hearing loss on the other side. A tympanoscopy and closure of the connection between the tympanic cavity and the internal auditory meatus stopped the ascending infections.

Adolescent↗
PubMed1986

[Methodological aspects of the use of the hydrogen (H2) breath test].

Normalization of the breath hydrogen (H2) concentration by simultaneous determination of breath carbon dioxide (CO2) and the addition of lactulose to a liquid meal have been recommended to improve the reproducibility of the hydrogen breath test. To assess the clinical relevance of these recommendations, we studied 64 children of 4 different age groups and 12 adults. Simultaneous determination of CO2 concentration and normalization of breath H2 resulted in a marked decrease of intestinal transit time and its variation in children; in adults, however, this correction was negligible. With lactulose alone, the mean coefficient of variation within individuals was only 11.7% and 13.2%, with and without H2 normalization, respectively. Therefore, the addition of a liquid meal does not seem to be necessary.

Adolescent↗