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Biomedical subjects

A R Alvarez

Publications and source records attributed to A R Alvarez.

11 recordsLinked to original sources
PubMed1989

[Severe asthmatic crisis in children].

The aim of the present study was to evaluate clinical and laboratory features of acute severe asthma (ASA) in children and their outcome of mechanical ventilation (MV). Twenty ASA episodes admitted to the hospital with hypercapnia (HC) and/or lost of consciousness (LC) and/or severe non reversible bronchial obstruction (NRBO) were retrospectively studied. Long lasting asthma and frequent admissions were registered in the majority of cases. In HC group (14 cases) the PaCO2 was 70 +/- 26 mmHg (X +/- SD). Hypercapnia was associated with intravenous administration of sodium bicarbonate in three cases. In NRBO group (4 cases) the acute response to salbutamol brought out during the first week of treatment and it was associated with increased basal forced expiratory volume in one second (FEV1). Ten cases were treated with MV because of hypercapnia and/or lost of consciousness, seizures (one case), and cardiac arrest (one case). The later patient died in 24 hours. Pneumothorax and atelectasis (one case), and pneumonia (one case) were the complications of mechanical ventilation. Three cases with PaO2 less than 60 mmHg and four cases with FEV1 less than 60% were sent home. After 27 days one patient from the later group had a new episode of ASA. Arterial gases and expiratory flow measurements are paramount tools for close monitoring of children with ASA. It is suggested that normalization of those parameters are an essential criteria for discharging those patients.

Adolescent↗
PubMed1977

[Erythropoiesis in the mouse following chronic administration of small doses of busulphan (author's transl)].

After both splenectomized and non-splenectomized mice had received a total amount of five doses of Busulfan at a rate of 0.14 mg/48 h, the recovery of their erythropoietic organs through the addition of 59Fe was investigated, after the cytostatic treatment had been cut off. In the non-splenectomized animals recovery was clear, keeping high 59Fe uptake values, significantly above normal, throughout the 21 days of the experiment. In the splenectomized mice, 59Fe uptake reached a peak of 38 per cent three days after the supply had been cut off, and from then on it descended to subnormal values.

Animals↗
PubMedDate not supplied

[Disease of the first permanent molar in Cuban children. An epidemiological problem].

The condition of first permanent molars in a cohort of children born in Cuba, during the week comprised from March the 1st. to 7, 1973, is presented now when they are 11 years old. Maxillary teeth presented a better conservation level than mandibular teeth. Non valuable differences were found in the condition of teeth of one or another hemiarch. It was found that 80.9% of the children had one or more molars affected by caries.

Child↗