Virilizing nodular ovarian stromal hyperthecosis, diabetes mellitus and insulin resistance in a postmenopausal woman. Case report.
Explore the source record for details and available documents.
Aged↗
Biomedical subjects
A R Bierre
Publications and source records attributed to A R Bierre.
Lambda-light-chain-mediated anti-GBM disease.
A 77-year-old man presented with macroscopic haematuria and oligo-anuric renal failure. A renal biopsy showed moderate linear glomerular basement membrane (GBM) staining with lambda light chains alone, but both circulating IgG and lambda light chain activity were present. There was no evidence of a serum or urinary paraprotein and a bone marrow biopsy was normal. Serum lambda light chains did not bind to renal GBM when examined by indirect immunofluorescence. This case suggests that light chains are capable of binding directly to epitopes in the GBM and may initiate injury although by a different mechanism from the IgG anti-GBM molecule.
Aged↗
Lung carcinoma presenting with systemic embolism: an uncommon differential diagnosis for atrial myxoma.
Explore the source record for details and available documents.
Carcinoma↗
Progression of hypertrophic cardiomyopathy to congestive cardiomyopathy: case report.
A case of hypertrophic cardiomyopathy presenting with chest pain and dyspnoea was followed for 18 years. During this time the patient showed a progressive loss of cardiac murmurs and over the last 12 months of life developed a dilatated cardiomyopathy associated with congestive heart failure, supraventricular and ventricular tachyarrhythmias.
Adult↗
Pulmonary fat and bone marrow embolism in aircraft accident victims.
On 28 November 1979, an Air New Zealand DC10 aircraft crashed into Mt Erebus, Antarctica with the loss of 257 passengers and crew. Postmortem examinations were carried out on 231 victims in Auckland, 4641 kilometres north of the crash site, and lung tissue was present in 205 cases. Pulmonary fat emboli were present in 134 cases (65%), pulmonary bone marrow emboli in 60 (29%) and pulmonary edema in 76 cases (37%). Clear relationships were demonstrated, firstly between the extent of fat and bone marrow embolism, secondly between the extent of fat and bone marrow embolism and the presence of pulmonary edema, and thirdly between the extent of fat and bone marrow embolism and the extent of cardiovascular damage. It was apparent that death had occurred immediately following impact, and the extent of fat and bone marrow embolism varied inversely with the severity of the injuries found. The most severely injured victims were those seated in the rear cabin of the aircraft suggesting that this was the site of impact with the ground. Our studies show that pulmonary fat embolism occurs very rapidly after severe injury and is followed by increasing numbers of fat and bone marrow emboli depending on the nature of the mortal injuries.
Accidents, Aviation↗
Mefenamic acid (Ponstan) induced interstitial nephritis.
Explore the source record for details and available documents.
Aged↗
Mercury levels in residents of a geothermal area in the Central North Island.
As a result of previous high trace metal findings in the soil, cattle, vegetation and water of the Broadlands area of New Zealand a study was made of the levels of mercury, selenium, arsenic and zinc in a group of children from this region. Arsenic and zinc levels were found to be normal but significantly raised urinary spot mercury concentrations were found in some of the children when studied in December 1975 and 24 hour urinary mercury concentrations recorded six months later were also raised, but to a lesser degree. Samples of household tap water showed increased mercury concentrations (median 0.001 micromol/L). In agreement with other New Zealand studies the blood selenium concentrations were low (76.7 mu/L) and they did not vary in relation to urinary mercury levels. The children were also examined for signs of peripheral neuropathy but only minor abnormalities were found. The source of the elevated mercury is uncertain but it may come from drinking water or possibly from locally produced meat or vegetables.
Adolescent↗
Papillary carcinoma in a thyroglossal duct cyst: CT findings.
A case of papillary carcinoma arising in a thyroglossal duct cyst is presented. The cystic mass may have a variable anatomic location: intralingual, suprahyoid, thyrohyoid, and suprasternal, along the course of the embryologic descent of the thyroid gland. Computed tomography allows characterization and precise identification of the extent of the lesion prior to surgical resection.
Adult↗