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A R Croft

Publications and source records attributed to A R Croft.

9 recordsLinked to original sources
PubMed1990

Legal implications of OSHA and CDC regulations.

The epidemic of acquired immunodeficiency syndrome has initiated a number of regulations, at both the federal and state level, that impact directly on the practice of dentistry. During the past 5 to 6 years, guidelines have been published that specifically and generally state those procedures which should be implemented in the dental practice with regard to infectious disease control. However, confusion remains regarding these procedural guidelines and the differences that exist between municipal, state, and federal regulations. The ensuing discussion (1) reviews the historical background of the guidelines, (2) reflects on the current Occupational Safety and Health Administration guidelines as they relate to the dental practice, (3) summarizes the role of the regulatory agencies, (4) discusses federal and state statutes that have impact on the dental practitioner, and (5) describes the possible legal implications that these regulations may have on the dental practice.

Acquired Immunodeficiency Syndrome↗
PubMed1980

Pharmacological screening of new chemical entities in human subjects and methods of data handling.

1 A system is described for screening new chemical entities in normal human subjects, which is designed to search for novel drug actions at an early stage of drug development. 2 In single (subject) blind experiments, doses are increased incrementally from one subject to next, with immediate feed-back of results from each dose. 3 As many physiological variables as possible are recorded, for which a purpose-designed apparatus system was constructed, and connected to a computer. 4 To overcome problems of inter-subject variability, the need for sensitivity, and to identify drug-related effects from the mass of data generated, a novel data management system was developed, and physiological profiles of volunteer subjects were built up to provide control data. 5 Results from a validation experiment in which isoprenaline was infused intravenously at different rates are presented and discussed.

Dose-Response Relationship, Drug↗