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Biomedical subjects

A R Doster

Publications and source records attributed to A R Doster.

29 records · Page 2Linked to original sources
PubMed1988

Identification of Mycoplasma hyopneumoniae in formalin-fixed porcine lung, using an indirect immunoperoxidase method.

An indirect immunoperoxidase staining technique was evaluated for detection of Mycoplasma hyopneumoniae in formalin-fixed, paraffin-embedded porcine lung. Lungs from swine with induced (n = 4) or naturally occurring M hyopneumoniae infection (n = 31) were examined grossly, by light and immunofluorescent microscopy, and by an indirect immunoperoxidase test, using antibody raised in swine against M hyopneumoniae as the primary antibody. Organisms stained by the indirect immunoperoxidase method were identified in tissue sections as pleomorphic brown-staining structures corresponding to those observed with immunofluorescence. Mycoplasma hyosynoviae, M hyorhinis, and Acholeplasma laidlawii did not stain with the indirect immunoperoxidase method, using antibody raised against M hyopneumoniae.

Animals↗
PubMed1987

Trichosporonosis in two cats.

Infection with Trichosporon spp was diagnosed in 2 cats. In one cat, infection consisted of a granulomatous dermatitis and was concurrent with disseminated lymphoblastic lymphosarcoma. In another cat, urinary cystitis caused by T beigelii was diagnosed.

Animals↗
PubMed1984

Isolation of Streptococcus suis from swine in Nebraska.

Streptococcus suis was isolated from swine with localized and diffuse infections. The isolates (n = 121) were unable to grow in broth containing 6.5% NaCl. Their abilities to hydrolyze esculin were variable, as were their fermentative reactions in lactose, trehalose, raffinose, and inulin. Sorbitol was not attacked by any strain. Serologic reactions were obtained between the isolates and coagglutination reagents prepared from commercially available antisera to streptococcal groups D, R, or S.

Age Factors↗
PubMed1983

An ultrastructural study of bronchiolar lesions in rats induced by 4-ipomeanol, a product from mold-damaged sweet potatoes.

Repeated intraperitoneal injections of 4-ipomeanol in rats resulted in extensive degeneration and necrosis of nonciliated (Clara) bronchiolar epithelial cells. Subsequently there was necrosis and detachment of ciliated cells from the bronchiolar basal lamina. The remaining nonciliated cells divided and differentiated into ciliated epithelial cells and mature Clara cells. The ability of Clara cells to metabolize certain xenobiotics suggests that they may play an important role in the pathogenesis of pulmonary disease and neoplasia.

Animals↗
PubMed1982

Long-term effect of Bordetella bronchiseptica infection in neonatal pigs.

A total of 62 gnotobiotic pigs were inoculated with Bordetella bronchiseptica at 7 days of age. There were 25 noninoculated controls. Thirteen of the inoculated pigs were killed and 6 pigs which died were examined between 3 and 5 weeks after inoculations were done (group A). Of these 19 pigs, 16 had severe pneumonia and B bronchiseptica was isolated from the lungs of 17. The turbinates in most of the pigs appeared to have some atrophy. Four other pigs died of pneumonia after they were transferred to the floor in isolation rooms, and 9 inoculated pigs were examined at necropsy at about 112 days of age (group B). Bordetella bronchiseptica was isolated from 8 of the latter 9 pigs, and 7 of the pigs had pneumonic lesions. The turbinates all appeared normal. Thirty inoculated pigs (group C) were killed at 180 days of age. Of these, 22 had pneumonic lesions. Bordetella bronchiseptica was reisolated from the turbinates of 2 of 30 pigs, although the turbinates in all appeared normal. The noninoculated controls examined at necropsy at 3 to 5 weeks, 112 days, and 180 days of age did not have any pulmonic lesions, and their turbinates appeared normal. The inoculated pigs killed at 112 days of age gained an average of 0.25 kg/day, and the control pigs gained 0.31 kg. At 180 days of age, the inoculated pigs had gained 0.41 kg/day and the controls, 0.49 kg. Bordetella bronchiseptica infection in susceptible pigs can cause a severe pneumonia which can persist and reduce the growth rate.

Animals↗
PubMed1978

Effects of 4-ipomeanol, a product from mold-damaged sweet potatoes, on the bovine lung.

Cattle given intraruminal administration of 4-ipomeanol, a furanoterpenoid originally obtained from sweet potatoes infected with Fusarium solani (F. javanicum), developed a respiratory syndrome clinically and histologically indistinguishable from atypical interstitial pneumonia. There were edema and emphysema in the lungs and mediastinum. The maximum nonlethal oral dose of 4-ipomeanol was estimated to be between 7.5 and 9 mg/kg of body weight.

Animals↗
PubMedDate not supplied

Liposarcoma in a Canada goose (Branta canadensis).

A multicentric liposarcoma was identified in various skeletal muscles of a mature Canada goose. The light and electron microscopic appearance of the tumor is discussed in relation to the appearance of liposarcoma in other species.

Animals↗
PubMedDate not supplied

Cryptosporidia in the cloacal coprodeum of red-lored parrots (Amazona autumnalis).

Cryptosporidiosis was diagnosed in the cloacal coprodeum of two red-lored parrots (Amazona autumnalis). The parasites were adhered to the microvillus border of epithelial cells and their presence was associated with loss and atrophy of microvilli. Merozoites, trophozoites, gametes, and oocytes were identified with light and transmission electron microscopy. The coprodeal epithelium was hyperplastic and the lamina propria was infiltrated with moderate numbers of heterophils and lymphocytes.

Animals↗