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Biomedical subjects

A R Fawcett

Publications and source records attributed to A R Fawcett.

At least 19 recordsLinked to original sources
PubMed1997

Effects of the duration of lairage following transportation on the behaviour and physiology of farmed red deer.

Eight groups of five farmed red deer were transported by road for three hours, after which they were either slaughtered immediately (TO) or held in lairage for three, six or 18 hours (T3, T6 and T18). Liveweight loss increased with lairage time but hot carcase weight was unaffected. Deer spent much of the initial period in lairage standing stationary in 'alert' postures. After eight to 10 hours the proportions of time spent in various postures (standing stationary, moving and lying down) were similar to pre-journey values. None of the blood components associated with dehydration (packed cell volume, osmolality, total protein and sodium) changed significantly with lairage time. Compared with T0 deer, plasma creatine kinase activity was significantly decreased in T18 deer. Lairage time had no effect on skin damage, bruising or muscle glycogen content, although liver glycogen content increased with longer lairage time. Although lairage time had a statistically significant effect on muscle pHu (with T6 deer having the lowest values), the differences were small and none of the carcases had a pHu greater than 6-0.

Abattoirs↗
PubMed1995

Johne's disease in a herd of farmed red deer.

An outbreak of Johne's disease in a herd of farmed red deer was studied for four years. Serological, histopathological and cultural techniques were used to monitor the progress of the disease, and delayed type hypersensitivity skin tests were also applied. The results of the serological tests showed that they were poor predictors of future clinical cases and did not consistently identify animals harbouring mycobacteria. The histopathological methods provided a sensitive and specific means of confirming the infection. The skin tests had a low sensitivity and the results were poorly correlated with the serological results in seropositive animals. A vaccination policy was instituted which was accompanied by a change in the pattern of disease. Although the histopathological evidence suggested that the infection was still occurring, there was a marked reduction in the incidence of clinical disease. Vaccinated animals showed a good response to the skin test.

Animals↗
PubMed1990

A study of a restricted programme of strategic dosing against Fasciola hepatica with triclabendazole.

A restricted programme of strategic dosing with triclabendazole was used to treat a sheep flock with severe clinical fascioliasis. After five years the percentage of ewes passing fluke eggs was reduced from 49 per cent to less than 1 per cent, without the reappearance of clinical fascioliasis. It is suggested that this programme offers an efficient and practical means of controlling fascioliasis.

Animals↗
PubMed1983

Use of cupric oxide needles in the prophylaxis of induced copper deficiency in lambs grazing improved hill pastures.

Cuprix oxide needles as a single oral dose were administered to ewes in the prepartum period, and to one member of each pair of twin lambs at between three and five weeks of age when grazing hill pastures improved by liming and reseeding. Lambs derived from dosed or undosed ewes and treated at three to five weeks of age were maintained in normocupraemia and showed no signs of ill-thrift. Lambs derived from dosed or undosed ewes but not themselves dosed showed hypocupraemia and ill-thrift. The lambs derived from the dosed ewes took longer to become hypocupraemic, but showed only a transient benefit from the ewe treatment. The dosed ewes showed a delay in the onset of hypocupraemia compared with the undosed ewes but there were no definable differences in performance between the two groups.

Administration, Oral↗
PubMed1981

Further studies in the control of ovine fascioliasis by strategic dosing.

Three hill sheep flocks were used to study the effect of the strategic use of rafoxanide to kill liver flukes before they attained the adult egg-laying stage. The programme ran from 1973 to 1976. In November 1976 the programme was stopped in one flock but was continued in the other two, which were subsequently merged. The results of frequent whole flock monitoring since 1976, described here, showed that in both flocks the level of infection, as judged by the examination of faeces for the presence of Fasciola hepatica eggs, remained at a very low level. It is postulated that the adoption of a strategic dosing programme over a period of three to four years would limit egg deposition on pastures close to eradication levels and that several years without needing to use anthelmintics against liver flukes would ensue.

Animals↗
PubMed1979

A study of the effects of copper deficiency in Scottish blackface lambs on improved hill pasture.

One member of each pair of twin lambs from 37 five-and six-year-old Scottish blackface ewes, grazing reseeded pasture suspected of causing a molybdenum-sulphur induced copper deficiency in sheep, was given an injection of 12.5 mg copper calcium edetate at about eight weeks of age. Plasma copper concentrations of these lambs were maintained in the normal range by further injections of copper as required (treatment group). The remaining member of each twin pair received no copper therapy (control group). The control lambs and all ewes showed marked hypocupraemia throughout lactation, whereas the plasma copper concentrations of the treatment lambs, and also of single lambs with continuous access to unimproved hill grazings, remained normal. The live-weight gain of the treatment lambs was significantly greater than that of the control lambs, the difference in mean live-weights after 12 weeks being 2.5 kg. All lambs showed some degree of osteoporosis; this was most severe in the control lambs which had less dense bones and were also more susceptible to bone fractures and to disease. Differences between treatment and control lambs were also observed in haematological parameters and in fleece characteristics.

Animals↗
PubMed1977

A study of a strategic dosing programme against ovine fascioliasis on a hill farm.

In a farm-scale veterinary preventive programme run from 1973 to 1976 the use of rafoxanide (Flukanide; Merck Sharp & Dohme) in the prophylaxis of ovine fascioliasis resulted in a marked reduction in the percentage of ewes passing fluke eggs in the faeces and an absence of clinical cases of fascioliasis throughout these years. Three separate flocks of hill sheep were used in this study in which the aim of the dosing programme followed was to kill the majority of liver flukes (Fasciola hepatica) before they reached adult egg laying stage, thereby eliminating, or considerably reducing, the number of eggs passed on to the pasture.

Animals↗
PubMed1975

Investigation into diagnosis and treatment of cobalt deficiency in lambs.

The development of cobalt deficiency was studied in 30 Scottish Blackface lambs grazing pasture on a soil containing 0-17 ppm cobalt. By the end of an eight-week period 50 per cent of lambs were subjectively appraised as showing signs of cobalt deficiency. After a further period lasting four weeks, during which three groups of lambs were studied (one group, least affected by cobalt deficiency, acted as control, the second received a single cobalt bullet and the third received oral doses of 200 mg cobalt chloride at the beginning of the period and three weeks later). Mean urinary formiminoglutamic acid (FIGLU) concentrations were inversely related to serum vitamin B12 concentrations and increased from 0-08 to 0-20 mumole per ml in group 1, and decreased to virtually zero within one week of treatment in groups 2 and 3. The use of serum vitamin B12 and urinary FIGLU concentrations in the diagnosis of cobalt deficiency in sheep are discussed.

Administration, Oral↗