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Biomedical subjects

A R Goldstein

Publications and source records attributed to A R Goldstein.

15 recordsLinked to original sources
PubMed1998

Soft tissue ridge augmentation to correct an esthetic deformity caused by adversely placed implants: a case report.

A patient presented with two osseointegrated implants placed in a ridge deformity that had resulted from a traumatic injury during an automobile accident. The implant placement and subsequent restorative dentistry resulted in a poor esthetic result and difficult maintenance. Treatment included multiple soft tissue grafts to submerge the implants and augment the ridge. The patient was then restored with a conventional fixed partial denture.

Adult↗
PubMed1992

Long-term follow-up of childhood Henoch-Schönlein nephritis.

A study of long-term outcome of 78 subjects who had had Henoch-Schönlein nephritis during childhood (at a mean of 23.4 years after onset) shows that severity of clinical presentation and initial findings on renal biopsy correlate well with outcome but have poor predictive value in individuals. 44% of patients who had nephritic, nephrotic, or nephritic/nephrotic syndromes at onset have hypertension or impaired renal function, whereas 82% of those who presented with haematuria (with or without proteinuria) are normal. 17 patients deteriorated clinically from an initial assessment in 1971; 7 of these had apparently completely recovered in 1976. 16 of 44 full-term pregnancies were complicated by proteinuria and/or hypertension, even in the absence of active renal disease. These findings indicate that childhood Henoch-Schönlein nephritis requires long-term follow-up, especially during pregnancy.

Biopsy↗
PubMed1987

Parvovirus associated aplastic crisis in homozygous sickle cell disease.

Aplastic crises in homozygous sickle cell disease in Jamaica predominantly affect children and occur in epidemics. Of 67 cases in a cohort study of 314 children with homozygous sickle cell disease, 62 were attributable to human parvovirus infection. Affected children were aged 0.5-12.5 years, and the incidence rose to 28% by 10 years. No recurrences were seen. Symptoms and signs on presentation were attributable to the viraemia and acute anaemia. Asymptomatic thrombocytopenia was common. Blood transfusion was given in 54 cases (87%). Thirty eight children (61%) were admitted to hospital, 16 of whom were extremely ill on presentation and one of whom died soon after admission. Twenty four (39%) were managed as outpatients, 16 of whom were transfused. Parvovirus associated aplastic crisis is a self limited condition with excellent prognosis if diagnosed promptly and managed appropriately.

Anemia, Aplastic↗
PubMed1985

Ligament replacement with an absorbable copolymer carbon fiber scaffold--early clinical experience.

Eighty-two patients, average age 29 years, were surgically treated (during the period from April 1981 to July 1983) for both acute (8%) and chronic (92%) knee ligament instabilities. An absorbable copolymer-carbon fiber ligament prosthesis was used as a tissue scaffold. Seventy-five percent had anterior cruciate ligament reconstructions, 6% had anterior cruciate and posterior cruciate ligament reconstructions, 6% had just posterior cruciate ligament reconstructions, and 9% had other combinations of anterior cruciate ligament, medical collateral ligament, and lateral collateral ligament reconstructions. Preoperative and postoperative evaluation, consisting of questionnaires, physical examinations, and isoskinetic testing, revealed significant improvements in categories of stability, pain, function, and strength persisting to the end of the study at 24 months. Arthroscopic examination and histologic studies of retrieved specimens demonstrated well-vascularized reconstructions with collagenous tissue ingrowth into the carbon-copolymer implants.

Adolescent↗
PubMed1984

Retained ligature wire and periodontal health. Report of a case.

Routine radiographic evaluation 15 years after orthodontic treatment revealed a circumferentially placed ligature wire situated at the crest of bone on the upper right lateral incisor. The wire was surgically exposed via a modified Widman flap technique and subsequently removed without adverse consequences relative to esthetics or periodontal support. It is of interest that the retention and location of this wire over such a long period of time resulted in no loss of periodontal support, especially since circumferential ligature placement is used experimentally to help promote periodontal breakdown.

Adult↗
PubMed1983

Accelerated periodontal disease in a patient with essential mixed cryoglobulinemia.

A 32-year-old woman diagnosed as having Type III essential mixed cryoglobulinemia presented with a history of gingival swelling and hemorrhage. Further clinical findings, in addition to sequential radiographs, revealed the presence of an unusual case of rapidly progressive periodontitis. An association between the presence of cryoglobulinemia and the periodontitis is implicated.

Adult↗
PubMed1980

Prior abortions and neural tube defects.

Out of a series of 219 women who had had a child with anencephaly or spina bifida (ASB) in the Manchester area, there were 69 where this ASB pregnancy had been both preceded and succeeded by at least one other pregnancy. There was a significant excess of spontaneous abortions when the preceding pregnancy was compared with the succeeding pregnancy. Half of these abortions were followed by curettage of the uterus, a fact which is a little against the trophoblastic rest hypothesis.

Abortion, Incomplete↗
PubMed1976

Acute effects of terbutaline and epinephrine on asthma. Double-blind crossover placebo study.

In order to assess the efficacy and safety of subcutaneous terbutaline 0.25 mg and 0.5 mg as compared to subcutaneous epinephrine, 28 stable asthmatics were studied. After control of environmental exposures in the clinical research facility at the University Hospitals of Case Western Reserve Medical School, the patients were entered into a double-blind crossover placebo-controlled 4-day study. All of the patients showed significant responses to both doses of terbutaline and after epinephrine as compared to placebo (greater than 15% increase in FEV1). In general, the side effects experienced were similar for 0.25 mg epinephrine and 0.25 mg terbutaline. They were slightly more pronounced with 0.5 mg of terbutaline. In terms of duration of action, there was a substantial difference between the duration of effect of subcutaneous epinephrine and subcutaneous terbutaline at both dosages. No cardiovascular side effects of any significance were noted in this study with either agent. We conclude that subcutaneous terbutaline is at least as effective as epinephrine in the management of reversible bronchospasm and may be considered a drug of choice in stable asthmatics.

Adolescent↗