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Biomedical subjects

A R Kerr

Publications and source records attributed to A R Kerr.

At least 55 records · Page 3Linked to original sources

Anaesthesia with profound hypotension for middle ear surgery.

To produce a blood-free field for middle ear surgery performed with the operating microscope, the arterial systolic pressure was reduced to less than 50 mm Hg in 700 patients by means of thiopentone-halothane-nitrous oxide in oxygen anaesthesia together with pentolinium tartrate. In 84% the results were excellent, in 12% moderately good and they were poor in 4%. There were more unsatisfactory results in males (22.8%) than in females (11.4%). In spite of the arterial pressure being reduced to very low values in many instances, there was no mortality or morbidity which could be ascribed to the technique.

Adult↗

Isolated mitral replacement with stent-mounted antibiotic-treated aortic allograft valves.

The results of valve replacement with a stent-mounted antibiotic-treated aortic allograft valve are reported in 129 patients with isolated mitral valve disease. Of these patients, 70 per cent were in N.Y.H.A. Class IV. The hospital mortality rate was 3.9 percent. The cumulative complication-free rate at 5 years was only 37 percent as 21 percent died late, a further 15 percent were alive following reoperation, 4 percent had an embolic episode, 4 percent were alive with important incompetence, and 20 percent had unimportant incompetence. Proved valve failure was due mainly to detachment of the aortic wall remnant of the valve from the pillar of the rigid metal stent (16 percent incidence at 5 years) and methods for preventing this complication are discussed. Because of these complications the use of this device in the mitral position has been discontinued.

Adolescent↗