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Biomedical subjects

A R Khosravi

Publications and source records attributed to A R Khosravi.

6 recordsLinked to original sources

Dermatophytes isolated from domestic animals in Iran.

Between 1994 and 1998, a total of 790 feather, hair and skin specimens from a variety of animals with suspected dermatophytoses were studied, of which 248 (31.4%) yielded dermatophytes. The most frequent dermatophytes isolated were Microsporum canis (38.3%), Trichophyton verrucosum (31.8%), T. mentagrophytes (13.3%) and M. gypseum (7.7%). There was a significantly higher proportion of positive cultures from cats (54.8%) than dogs (8.2%), and M. canis was the most common species isolated (87.2 and 50% respectively). Trichophyton verrucosum was the most frequent causative agent of dermatophytoses in ruminants, M. equinum in horses, M. gypseum in rabbits, M. gallinae in chickens and T. mentagrophytes in pet squirrels.

Age Factors↗

Onychomycosis in Tehran, Iran: prevailing fungi and treatment with itraconazole.

A total of 187 Patients with suspected onychomycosis were examined for causative fungal agents between 1996 and 1997. Laboratory examination confirmed onychomycosis in 115 patients, of which 97 cases were presented with positive microscopic and cultural examinations, and they were selected for itraconazole pulse therapy. From an etiological point of view, 48.4% of the nail infections, mainly toenail infections, were caused by dermatophytes, 43.3% were infected with Candida spp, specially infected fingernails, and 8.2% by non-dermatophytic molds. Trichophyton mentagrophytes var. interdigital and T. violaceum were the most prevalent species. Candida albicans and C. parapsilosis were the predominant species of the Genus Candida. Scopolariopsis brevicaulis was the most common non-dermatophyte molds observed. Female affected more frequently than male and in both sexes, those who were 30-49 years old, more infected. Toenails were affected more frequently than fingernails. In this study, itraconazole pulse therapy (400 mg daily) gave during the first week of per month for 3 months. The study included 51 patients with toenail onychomychosis (group 1) and 46 patients with fingernail infections (group 2). Patients were followed up for 9 months after the last treatment. Clinical response rates were 83% in the group 1, 95% in the group 2 at month 12; the corresponding mycological cure rates were 71 and 87%, respectively.

Adolescent↗

Isolation of Cryptococcus neoformans from pigeon (Columbia livia droppings in northern Iran.

Nine hundred and eighty three specimens of pigeon droppings, collected in different regions of northern Iran, were examined. Of these samples, 175 (17.8%) were positive for Cryptococcus neoformans. All isolates obtained were C. neoformans var. neoformans. Most of these isolates of C. neoformans were from pigeon shelters. There were significant differences in isolation frequency between pigeon shelters and the other collection sites.

Animals↗

Dermatophytoses in Iran.

A total of 12,150 cases of suspected dermatophytoses in different areas of Iran were studied between 1986 and 1991. The age groups most commonly infected were 1-9 and 20-29 years. Clinical diagnosis was confirmed in only 9345 cases by laboratory examination. Of these positive samples, 1633 cases were found to be positive by direct microscopic observation only, 429 by culture only and 7283 by both techniques. Scalp ringworm of children was the most common type of tinea. But according to the rate of infection, tinea corporis, tinea pedis, tinea cruris, tinea manuum, tinea unguium and tinea barbae were the next most prevalent in that order. The frequencies of dermatophytes isolated from patients were as follows: Microsporum canis 19.4%, Trichophyton rubrum 16.5%, Epidermophyton floccosum 14.9%, Trichophyton mentagrophytes var. interdigitale 14.6%, Trichophyton verrucosum 11.5%, Trichophyton mentagrophytes 6%, Trichophyton violaceum 8.7%, Trichophyton schoenleinii 5.5%, Trichophyton tonsurans 1.3%, Trichophyton erinacei 0.8% and Microsporum gallinae 0.2%.

Adolescent↗

Fungal flora of the hair coat of stray cats in Iran.

The fungal flora of the hair coat of 100 stray cats in different districts of the city of Isfahan, Iran, were examined. Saprophytic fungi were isolated from all cats. Penicillium, Aspergillus, Alternaria, Mucor and Cladosporium spp. were the most frequently isolated saprophytes. Microsporum canis was isolated from all kittens with clinical signs of dermatophytosis. In other cases, M. canis was isolated only from 22 of the 96 cats. No significant differences in sex, hair length, and fungal flora of the hair coat were found between the M. canis-infected and M. canis-free cats.

Alternaria↗