Nutritional circulation in the heart. I. Effect of change in heart rate on myocardial oxygen consumption and nutritional circulation with constant total coronary blood flow.
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Animals↗
Biomedical subjects
A R Laddu
Publications and source records attributed to A R Laddu.
Structure-activity relationship of the beta adrenoreceptor blocking agents.
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Adrenergic beta-Antagonists↗
Nutritional circulation in the heart. II. A reappraisal of the effect of nitroglycerin on myocardial hemodynamics, oxygen consumption and nutritional blood flow in the isolated supported heart preparation.
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Animals↗
Desipramine toxicity and its treatment.
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Animals↗
Blockade of cardiac effects of isoproterenol by 4-(2-hydroxy-3-isopropylaminopropoxy)-acetanilide (ICI 50,172).
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Acetanilides↗
Antiarrhythmic actions of 4-(2-hydroxy-3-isopropylaminopropoxy)-acetanilide (ICI 50,172) in the dog heart-lung preparation.
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Acetanilides↗
Effects of newer glucocorticoids on anaphylactic shock in the rat and the mouse.
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Anaphylaxis↗
The physiological levels of histamine in human tissues.
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Age Factors↗
Corticosteroids and experimental allergy.
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Anaphylaxis↗
Cardiovascular and neuromuscular effects of esmolol during induction of anesthesia.
Sixteen subjects scheduled for surgical procedures under general anesthesia participated in an investigation of the effects of esmolol on the transient hypertension and tachycardia that was observed during endotracheal intubation and on the duration of succinylcholine-induced neuromuscular blockade. In eight subjects, infusion of esmolol was begun five minutes before induction of anesthesia and continued for 12 minutes after induction. In the remaining subjects, an equivalent volume of solvent (D5W) was infused for 12 minutes. Infusion of esmolol significantly attenuated the cardioacceleration observed during intubation without any significant effect on the pressor effects of the procedure. Esmolol delayed the recovery from succinylcholine-induced neuromuscular blockade by less than three minutes. The mechanism of this delay remains to be investigated, although such a delay does not have clinical significance. Esmolol-induced attenuation of the tachycardia seen during intubation may offer a protective effect on the myocardium, especially in elderly subjects and patients with coronary artery disease.
Adrenergic beta-Antagonists↗