PubMed Health⌕ Search

Biomedical subjects

A R Luksza

Publications and source records attributed to A R Luksza.

9 recordsLinked to original sources
PubMed1987

Peripheral blood eosinophil counts and bronchial responsiveness.

Bronchial responsiveness (histamine PC20) and peripheral blood eosinophil counts were measured in 23 asthmatic subjects, of whom 14 were atopic and nine non-atopic. In the group as a whole there was an inverse correlation between baseline eosinophil count and histamine PC20 (r = -0.71; p less than 0.001). For atopic subjects a relationship between eosinophil count and histamine PC20 was observed (r = -0.74; p less than 0.01), but there was no correlation between eosinophil count and baseline FEV1 or baseline FEV1 and histamine PC20. For the non-atopic subjects a similar relationship between eosinophil count and histamine PC20 was seen (r = -0.68; p less than 0.05) and a less significant inverse correlation between baseline eosinophil count and baseline FEV1 (r = -0.65; p less than 0.05). These results show a relationship between eosinophil count and non-specific bronchial responsiveness in both atopic and non-atopic asthma.

Adolescent↗
PubMed1987

Training schemes in medicine at two district general hospitals.

After 40 years, NHS planning still results in medical overmanning or shortages. The training schemes in medicine described have, for 25 years, avoided the worst errors. Success has depended on the following triad: a realistic view of career prospects, Osler's master word--work, and systematic clinical research.

Hospitals, General↗
PubMed1986

Acute severe asthma treated by mechanical ventilation: 10 years' experience from a district general hospital.

A retrospective study was made of patients requiring mechanical ventilation (intermittent positive pressure ventilation--IPPV) for acute severe asthma in a district general hospital during 1974-83. Thirty two patients required IPPV on 34 occasions. Complications included pneumothorax in six (18%) patients, chest infection in 12 (35%) patients, pulmonary collapse in three (9%) patients, hypotension at induction of IPPV in 12 (35%), and gastrointestinal bleeding in three (9%). Three (9%) patients died. Therapeutic bronchial lavage was performed in 19 patients. The procedure produced a rise in effective static compliance from a mean of 17 (SD 6) ml/cm H2O to 24 (9) ml/cm H2O at four hours. Bronchial lavage was associated with a significant excess of respiratory infections. A feature common to most patients was undertreatment before admission to hospital.

Acute Disease↗
PubMed1984

Influenza B virus infection complicated by pneumonia, acute renal failure and disseminated intravascular coagulation.

The case is presented of a 14-year-old boy in whom influenza B virus infection caused pneumonia, acute renal failure and disseminated intravascular coagulation (DIC). Survival was achieved by prompt treatment of DIC with clotting factors and heparin. DIC should be diligently sought in severe viral infections because appropriate therapy may be life-saving.

Acute Kidney Injury↗
PubMed1983

Successful treatment of meningitis with cefotaxime in an adult.

A case of severe bacterial meningitis complicated by alcoholism, lobar pneumonia and coma, is described. Although triple antibiotic therapy had been ineffective, the patient made a rapid and complete recovery when treated with cefotaxime alone.

Cefotaxime↗
PubMed1979

Saving asthmatics.

Explore the source record for details and available documents.

Acute Disease↗
PubMed1979

Brain-dead kidney donor: selection, care, and administration.

Over four and a half years a district general hospital provided 34 cadaveric kidneys for transplantation. All brain-dead patients were regarded as potential donors, flow charts being used to maintain circulation and urine formation and facilitate administration. With this system the time lapse between diagnosis of brain death and removal of kidneys ranged from three to six hours and ischaemia was minimised. It is concluded that adoption of the system by other hospitals of comparable size would result in enough good-quality kidneys to satisfy present needs, thus reducing the initial high failure rate and enabling more patients to be accepted for dialysis.

Brain↗