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Biomedical subjects

A R Quayle

Publications and source records attributed to A R Quayle.

10 recordsLinked to original sources
PubMed1992

Primary lymphoma of the thyroid, the association with Hashimoto's thyroiditis.

This paper reviews the cases of thyroid lymphoma seen at one centre to assess the relationship between autoimmune thyroiditis and the subsequent development of thyroid lymphoma. Twenty two cases of thyroid lymphoma were seen over a 10 year period; 5/22 (23%) had previously been diagnosed as having Hashimoto's thyroiditis. The series comprised 18 women and four men; mean (range) age at presentation was 64 (26-85) years. All patients presented with a rapidly enlarging goitre and 13/22 (59%) underwent surgical excision prior to diagnosis of lymphoma. Nineteen of 22 (86%) patients underwent radiotherapy. The 5-year mortality for stage IE disease was 43%, survival appeared to be unrelated to previous Hashimoto's thyroiditis or to surgical resectability. The histological differentiation between pre-existing thyroiditis and thyroid lymphoma is often difficult and may lead to an underestimate in the reporting of the association. A prospective study of serial autoantibody assays in patients with Hashimoto's thyroiditis may be useful in predicting the onset of lymphomatous change in this condition.

Adult↗
PubMed1990

The association between thyroid neoplasia and intestinal polyps.

Recent reports have suggested an association between familial adenomatous polyposis and papillary carcinoma of the thyroid. This report describes four patients, each with intestinal polyps and thyroid or thyroglossal cyst carcinoma. One patient had a medullary rather than papillary carcinoma of the thyroid and in another the intestinal polyps were due to Peutz-Jeghers syndrome. This may indicate a wider association between thyroid carcinoma and intestinal polyps than has previously been recognised.

Adult↗
PubMed1985

Jejunal perforation secondary to metastatic bronchogenic carcinoma.

A case of peritonitis secondary to the perforation of a bronchogenic small bowel metastasis is reported. To our knowledge this is only the fourth case in which peritonitis was the presenting feature of a squamous cell carcinoma of the bronchus. The publications to date are reviewed and the need to biopsy every small bowel perforation found at laparotomy is stressed.

Aged↗
PubMed1985

Treatment of oesophageal perforation by intubation.

The mortality following oesophageal perforation ranges from 25% to 100% depending on the delay in diagnosis and treatment. Although the treatment recommended for thoracic perforations is emergency thoracotomy and suture of the perforation, the avoidance of this approach in elderly patients is desirable. We therefore describe 6 cases of oesophageal perforation which were treated by insertion of a Celestin tube at laparotomy.

Aged↗
PubMed1985

Cystadenoma of the pancreas--an unusual presentation.

Cystadenoma is a rare lesion of the pancreas. A case is reported in which the tumour was initially misdiagnosed as a pseudocyst and inappropriate surgery performed. The patient subsequently presented with gastro-intestinal haemorrhage and the tumour was resected. The diagnosis and management of cystic lesions of the pancreas are discussed, stressing the need for complete pre-operative investigation in order that incorrect treatment is avoided.

Cystadenoma↗