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Biomedical subjects

A R Rodríguez

Publications and source records attributed to A R Rodríguez.

2 recordsLinked to original sources

[Introduction and development of local anesthesia in Spain].

This study was carried out to identify key events in the history of the introduction and evolution of techniques for local anesthesia in Spain. We searched Spanish archives, finding a large number of documentary evidence, most of which is unpublished or has not been cited by other authors. Analyzing these documents with methods usually applied by medical historians, we found that techniques of local anesthesia were put into practice rapidly and widely and that they were an important factor in the development of Spanish surgery, as anesthesia made both the undertaking and the success of many procedures a real possibility.

Anesthesia, Local

Experimental smallpox in chimpanzees.

In an attempt to prepare highly specific antiserum to variola virus, a chimpanzee was inoculated with a virulent human strain of this virus. Three uninoculated chimpanzees were housed in the same room; two of these developed clinical disease with seroconversion, while the third developed no evidence of infection and no antibody. The three animals that became ill also developed antibody to vaccinia and monkeypox viruses. Human contacts during the study and following a break in containment showed no evidence of infection as determined by serological tests and lack of clinical disease.

Animals