Biomedical subjects

A R Whittaker

Publications and source records attributed to A R Whittaker.

3 recordsLinked to original sources

PubMed2005

Automatic wheeze detection based on auditory modelling.

Automatic wheeze detection has several potential benefits compared with reliance on human auscultation: it is experience independent, an automated historical record can easily be kept, and it allows quantification of wheeze severity. Previous attempts to detect wheezes automatically have had partial success but have not been reliable enough to become widely accepted as a useful tool. In this paper an improved algorithm for automatic wheeze detection based on auditory modelling is developed, called the frequency- and duration-dependent threshold algorithm. The mean frequency and duration of each wheeze component are obtained automatically. The detected wheezes are marked on a spectrogram. In the new algorithm, the concept of a frequency- and duration-dependent threshold for wheeze detection is introduced. Another departure from previous work is that the threshold is based not on global power but on power corresponding to a particular frequency range. The algorithm has been tested on 36 subjects, 11 of whom exhibited characteristics of wheeze. The results show a marked improvement in the accuracy of wheeze detection when compared with previous algorithms.

Algorithms↗

PubMed2001

Breath sounds, asthma, and the mobile phone.

The sounds generated by breathing in asthma are widely accepted as an indicator of disease activity. We have investigated the use of a mobile phone and electronic signal transfer by e-mail and voice mail to study tracheal breath sounds in individuals with normal lung function and patients with chronic or exercise-induced asthma. Spectrograms from patients with active asthma and impaired lung function were significantly different from people without asthma (p<0.0001). Our results suggest that mobile phone recordings clearly discriminate tracheal breath sounds in asthma and could be a non-invasive method of monitoring airway diseases.

Adolescent↗

PubMed2000

Limitations in the use of median frequency for lung sound analysis.

The aim of this paper is to investigate methods of standardizing lung sound analysis, with a view to supplementing traditional spirometric air flow measurements to help in the diagnosis of asthma and to provide a measure of the effectiveness of treatment. Lung sounds were measured in nine patients with asthma and five control subjects, alongside air flow measurements of forced expiratory volume (FEV1) and forced vital capacity (FVC). The patients were administered the bronchodilator, salbutamol, to assess how effective these measurement techniques were for quantifying its effect. The results agree with previous studies, that analysis of lung sounds is a potentially useful tool for indicating air flow changes. The results, however, also demonstrate that the emerging standard of 'F50' or 'median frequency' should be treated with great caution because of its high sensitivity to the measurement frequency range. F50 is very unlikely to provide a reliable single indicator of lung condition.

Adolescent↗