Biomedical subjects
Publications and source records attributed to A R Youssef.
Twenty women studied for diagnostic or therapeutic laparoscopy with intraperitoneal insufflation of carbon dioxide. There were circulatory changes, dysrrhythmias, elevated central venous pressure and arterial blood pressure, hypercarbia, decrease in pH and increased peak air way pressure. With abdominal decompression all changes returned to within normal values.
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Four analgesic agents were studied during labour: pethidinesparine, ketamine hydrochloride, nitrous oxide-oxygen, and trichloroethylene in air (Trilene). Excellent analgesia was achieved with ketamine, however hallucinations were troublesome. Trichloroethylene analgesia was good without side-effects. Pethidine-sparine produced moderate analgesia but with nausea and/or vomiting. Nitrous oxide 50% presented poor analgesia. Uterine activity was insignificantly diminished in the late first stage after administration of all analgesic agents except with ketamine. There were no untoward effects on fetuses.
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