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Biomedical subjects

A Rüttimann

Publications and source records attributed to A Rüttimann.

At least 19 recordsLinked to original sources
PubMed1996

The substrate specificity of tocopherol cyclase.

The substrate specificity of the enzyme tocopherol cyclase from the blue-green algae Anabaena variabilis (Cyanobacteria) was investigated with 11 substrate analogues revealing the significance of three major recognition sites: (i) the OH group at C(1) of the hydroquinone, (ii) the (E) configuration of the double bond, and (iii) the length of the lipophilic side chain. Experiments with two affinity matrices suggest that substrates approach the enzyme's active site with the hydrophobic tail.

Chemical Phenomena↗
PubMed1986

[Cavernous bronchus carcinoma].

In thoracic surgery patients the etiology of cavities has drastically changed in the last 20 years. While at present only very few patients need surgery for cavernous tuberculosis, cavities of cancerous origin are becoming more and more frequent. During the period from 1977 to 1985 24 out of 225 bronchogenic carcinomas treated by resection were found to be cavernous (10.7%). Radiologically the degree of cavitation extended from a small marginal or central air collection to the formation of large, irregular, and thick-walled caverns. The excavation is the result of necrobiotic changes within the tumor. It arises when the tumor masses penetrate into the bronchial tree and are expectorated. However, prognosis of cavitated cancer remains exclusively dependent on the stage of the tumor. The cavitation itself seems not to influence it.

Carcinoma, Bronchogenic↗
PubMed1976

[The differentaition between malignant and benign lesions by retrograde pancreaticography].

The accuracy of ERCP in the differentiation between carcinoma of the pancreas and chronic pancreatitis is evaluated in a series of 39 cases with proved final diagnosis. The specificity of 6 different morphological types of duct alterations for carcinoma or for chronic pacreatitis is analyzed. - The accuracy of differentiation was 90% in the present series. Long, irregular stenosis or localized destruction of ductal branches were found in carcinoma only. Short, smooth stenosis or diffuse duct alterations were present in pancreatitis only. Total obstruction was found in both diseases in about the same frequency.

Adult↗