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Biomedical subjects

A Ricardo

Publications and source records attributed to A Ricardo.

3 recordsLinked to original sources

[Acute monoarthritis and laryngeal obstruction as extralymphatic manifestations of non-Hodgkin's lymphoma].

Joints and larynx are uncommonly involved by non-Hodgkin's lymphoma (NHL). Synovial involvement has been reported in only 7 cases, mainly located in the knees. When this is the first location of NHL it is usually misdiagnosed. The treatment of choice is local radiotherapy followed by systemic chemotherapy. Laryngeal lymphoma can be either primary or forming part of multifocal disease. The prognosis of the primary form is usually good only with radiotherapy, whereas the prognosis of the laryngeal location of advanced disease is rather poor. The symptoms include dysphonia and slowly progressive dyspnea. A case of NHL is presented who showed initial arthritis of the knee, later evolving into severe laryngeal obstruction, an association not previously reported.

Acute Disease↗

[Hyperplastic polyp of the colon].

On re-examining 477 polyps of the colon obtained by endoscopic polypectomy, the authors describe a type of polyp with they have called hyperplasiogenous. This polyp is characterised by a proliferation of rectilinear glands, divided at their base, forming a connecting spur; this spur may form a more complex alveolar or tubulo-alveolar structure. The glands have cells with a tall, clear cytoplasm and a small, homogeneous nucleus with no irregularities or metaplasia. Endoscopically, they are small, sessile and either the same colour as the mucous membrane or redder. They are located mainly in the rectum and sigmoid colon. They are more frequently found in men and begin to appear after the age of thirty. They are often associated with tumours of the colon. The authors consider possible that the hyperplasiogenous polyp may represent an initial stage of adenoma.

Adult↗