PubMed Health⌕ Search

Biomedical subjects

A Rintala

Publications and source records attributed to A Rintala.

At least 37 records · Page 2Linked to original sources
PubMed1982

Increasing incidence of clefts in Finland: reliability of hospital records and central register of congenital malformations.

The treatment of cleft lip and/or palate [CL(P), CP] in Finland has been centralized to one unit since 1947. Since 1963 all congenital malformations are reported to a central register. Comparison of these two materials showed that altogether 3928 children with clefts, born from 1948 to 1975, were registered in a total of 2 258 850 live born children in Finland, corresponding an incidence of 1.74%. There was a constant registered rise in the incidence from 1.31% in 1948-52 to 2.16% in 1969-75, indicating a corrected "true" increase in the incidence by 33% in 28 years, or approximately by over one percent per year. Of all registered clefts born 1963-75 23.5% were lacking from the Register of Congenital Malformations, and 10.3% from the hospital records. In 1948-75 55.8% of the clefts belonged to the group CP and 44.2% to CL(P). The incidence of CP increased from 0.78% in 1948-52 to 1.21% in 1969-75, and that of CL(P) from 0.53 to 0.95%. An average of 13,8% of the CP-cases were submucous clefts. Their registered incidence in all live born children increased from 0.08% in 1948-52 to 0.19% in 1969-75.

Adolescent↗
PubMed1982

Familial intra-areolar polythelia with mammary hypoplasia.

Dysplastic divided nipples (intra-areolar polythelia) have been found bilaterally in a mother, her two daughters and one son. Two of the patients had mammary hypoplasia, one had unilateral hypoplasia of the pectoral muscle and duplication of the renal pelvis and ureter. The mammary findings are consistent with autosomal dominant inheritance. Whether they represent a new mammo-renal syndrome is uncertain. Reconstructive surgery was performed on two patients. Due to the deformity the mother was unable to nurse her children; following reconstructive surgery the daughter was able to feed her baby normally.

Adult↗
PubMed1980

Oblique facial clefts: case report.

In a material of about 3,600 facial clefts eleven oblique clefts were observed (3.1%). The most frequent types were the medial oro-ocular and naso-ocular clefts and their combinations. There were two atypical cases and one lateral oro-ocular variety. The oblique clefts were frequently associated with other types of clefts and/or more distant anomalies. No genetic chromosomal or environmental factors were found to explain their etiology. Amniotic bands could possibly be thought to be responsible for the severe malformations in two instances. The lacrimal apparatus was always involved to some degree with the exception of a few incomplete forms. In the alveolar arch the cleft seemed to be situated between the medial incisor and the canine.

Adult↗
PubMed1979

The effect of the lip adhesion procedure on the alveolar arch. With special reference to the type and width of the cleft and the age at operation.

In a material of 89 wide clefts, we measured the effect of the lip adhesion on the width of the cleft, the deviation of the maxillary arch segments, and in bilateral clefts on the premaxillary protrusion. The width of the unilateral complete cleft diminished by two-thirds, on average, depending upon decreasing positive deviation of the major alveolar segment, while the minor segment did not react at all. In unilateral alveolar clefts the effect was in principle similar. In bilateral complete clefts the width of the cleft diminished by only 40-50%, on the average, and the protrusion of the premaxilla by 8-23%, while the primarily always negative segmental deviation decreased by about 40%. The age at operation within certain limits did not seem to influence the results in any significant way. Lip adhesion is thus recommended especially in wide unilateral complete clefts as an operative orthodontic procedure to facilitate subsequent final repair.

Age Factors↗
PubMed1978

Anophthalmia and agenesis of columnella, prolabium and premaxilla without hypotelorism-a new syndrome? Case reports.

Three patients with a syndrome consisting of anophthalmia, midline upper lip pseudocleft with absent columnella, prolabium and premaxilla, but without hypo- or hypertelorism are presented, together with three borderline cases with an- or microphthalmia and lacking distal half of the nose or cleft lip and palate. The pathogenesis and relations to other facial anomalies are discussed.

Abnormalities, Multiple↗
PubMed1976

On the [4-14C]progesterone metabolism of keloid and hypertrophic scar. A preliminary report.

Tissue specimens from keloids (K) and hypertrophic scars (H), as well as from the healthy skin in their vicinity (KS resp. HS) were incubated in a medium containing [4-14C]progesterone. The metabolites were isolated and verified with thin layer chromatography. All investigated tissue types produced as metabolites of progesterone 5 alpha-pregnane-3,20-dione, 5 alpha-pregnane-3 alpha, 20 alpha-diol, as well as probably 3 alpha/beta-hydroxy-5-pregnan-20 one. The diffusion of progesterone from the medium into the tissue was most effective in K, in sharp contrast to H. The ability of the tissue to take up progesterone from the medium was nearly double in HS as compared with KS. HS seems to metabolize progesterone nearly with the same effectivity as K, and those both twice as much as KS. There were also marked differences in the division of metabolites between the tissue and the medium.

Adolescent↗
PubMed1976

Innervation of human axillary sweat glands. Histochemical and electron microscopic study of hyperhidrotic and normal subjects.

Adrenergic nerves were demonstrated by formaldehyde-induced fluorescence and cholinergic nerves using thiocholine techniques to demonstrate acetylcholinesterase activities at the light and electron microscopic levels. The specimens were taken during surgery from the axillae of hyperhidrotic patients and normal voluntary controls. No fluorescent nerves were found around eccrine or apocrine sweat glands in hyperhidrotic or normally sweating axillae. Both eccrine and apocrine sweat glands exhibited a nerve network showing acetylcholinesterase activity. There was no marked difference in the innervation patterns or in the intensity of the acetylcholinesterase reaction of the nerves in the hyperhidrotic patients or normal subjects. Ultrastructurally the acetylcholinesterase-positive nerves were seen in the vicinity of both eccrine and apocrine glands, but these nerves were outside the basement membrane.

Axilla↗
PubMed1976

Bone formation with free periosteal grafts in reconstruction of congenital maxillary clefts.

In a series of 23 patients free grafts of tibial periosteum have been used in the reconstrlction of 26 congenital maxillary clefts. In 23 (88.5%) of these clefts, rapid bone formation occurred at the transplantation site overbridging the bone defect in 20 (77%) of the clefts. The permanent value of these bone bridges has not yet been solved. Nevertheless, this operation has demonstrated the strong osteogenic capacity of free periosteal grafts suggesting their use also in other fields, where bony fusion or reconstruction of other defects is needed.

Cleft Lip↗
PubMed1976

Tissue adhesive vs sutures in closure of incision wounds. A comparative study in human skin.

Two different standard incisions were used to compare the healing of wounds closed with normal "atraumatic" surgical technique and with a tissue adhesive. Healing was recorded by serial photography. It was found that wounds, which were not under tension postoperatively, the resulting scar was cosmetically better when tissue adhesive was used compared with conventional methods of suture.

Cleft Lip↗
PubMed1976

Ulcerating paraffinoma.

One case of an ulcerating paraffinoma of the male mammary gland and another of the penis are reported. The former is the third and the latter the eighth of its kind described in the literature. Psychopathological features were associated with both cases, and additionally impotence with the latter. The treatment of paraffinomas is surgical. Subcutaneous mastectomy was performed on the mammary gland, leaving a high proportion of the affected skin in situ. Recovery was slow and the cosmetic end result not satisfactory. Re-injection of paraffin later required total excision of the entire anterior thoracic skin and subcutaneous tissues and skin grafting. The penile paraffinoma was treated by complete excision and again subsequent skin grafting. Both the functional and cosmetic results of the latter were good.

Adult↗
PubMed1975

Treatment of familial benign chronic pemphigus by skin grafting.

A report on a patient with familial benign chronic pemphigus, resistant to all conservative therapy, treated in several stages by surgical excision of the most affected areas and reconstruction with split skin grafts. The follow-up period of the treated sites varies from two to eight years. All grafted sites have remained totally asymptomatic and there has been no sign of recurrence. Outside the grafted areas the disease is still as active as before.

Adult↗