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A Rodríguez Cuartero

Publications and source records attributed to A Rodríguez Cuartero.

At least 19 recordsLinked to original sources
PubMed2001

[Urinary glycosaminoglycans after extracorporeal shock wave lithotripsy in patients with kidney lithiasis].

OBJECTIVE: Extracorporeal shock wave lithotripsy (ESWL) is a technique that is not free of adverse effects. Renal changes detected during complementary exploratory procedures have been described, although these are minimal, resolve within a few days, do not present clinical manifestations and are not detected on ultrasound in most of the cases. For this reason, we studied a marker for renal injury, the urinary excretion of glycosaminoglycans (GAG) in patients with renal calculi, before, immediately after and 30 days following ESWL. The novelty of the study lies in that we have classified the patients with calculi according to the degree of renal function before ESWL, since it is recognized that the obstructive features of lithiasis can cause some degree of renal impairment. METHODS: Urinary GAG was quantified according to the colorimetric method described by Pennock. RESULTS: Urinary GAG levels were found to be lower in patients with renal calculi and preserved renal function than in healthy control subjects. In the presence of renal failure, these levels are elevated due to the obstructive nephropathy caused by calculi. Urinary GAG significantly increased post-ESWL in patients with renal lithiasis and preserved renal function or renal failure. At 30 days post-ESWL, GAG returned to pre-test levels. CONCLUSIONS: Quantification of urinary GAG is a useful biochemical method in the evaluation of renal parenchymal injury produced by ESWL.

Adult↗
PubMed1997

[Idiopathic hemochromatosis, analysis of 19 cases].

We studied 19 patients with idiopathic haemochromatosis between 12,000 patients by the Department of Internal Medicine. By 17 the diagnosis was made very late with severe state of chronic liver disease, only two went to consult because transaminases were increased without exploration in routinary examination. Hepatomegalie was constant exploratory feature (100%) followed by impaired hydrocarbonated metabolism (52%). The biochemical usual pattern was: hipersideremie, decreased transferrin and increased transaminases activities in all the patients. Increased iron urinary excretion (more than 8 g/24 h) with desferroxiamine administration is a useful biochemical feature if because severe liver disease the biopsy punction was not indicated due to impaired hemostasia. Because the serious illness with late diagnosis and the normal survival if the diagnosis is early the iron metabolism would be useful screening as in another countries.

Adult↗
PubMed1997

Plasminogen in patients with liver cirrhosis.

BACKGROUND: We studied the plasminogen concentration in patients with alcoholic liver cirrhosis in order to assess its synthesis in the liver and establish correlations with other routine parameters such as the albumin level and prothrombin time. MATERIAL AND METHODS: Plasminogen was determined by radial immunodiffusion albumin by nephelometry and the prothrombin time by Quick's method. The study involved 40 healthy volunteers and 80 patients diagnosed as having alcoholic liver cirrhosis. Histopathological confirmation was achieved in 56 patients, while in the remainder it was based on other instrumental methods and clinical and laboratory findings. RESULTS: The plasminogen level was lower in patients with liver cirrhosis (7.8 +/- 0.3 mg/dl) than in healthy controls (11.7 +/- 0.6 mg/dl). According to the Child-Pugh classification, the concentration in class A was 9.0 +/- 0.3 mg/dl, in class B it was 7.3 +/- 0.4 mg/dl and in class C it was 6.1 +/- 0.2 mg/dl. The differences between the groups were statistically significant. CONCLUSION: The plasminogen level is of diagnostic value in the assessment of liver function and correlates well with the albumin concentration and the prothrombin time.

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