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Biomedical subjects

A Rodríguez

Publications and source records attributed to A Rodríguez.

At least 253 records · Page 14Linked to original sources
PubMed1991

[Digital coronary angiography. A new approach in the analysis of the arteriosclerotic plaque].

In order to define the coronary lesions we prospectively performed digital coronary angiographies in 61 patients. The degree of stenosis was measured in 100 lesions by quantitative analysis using densitometric and geometric methods. Two groups of lesions were found by comparing these two methods: Group A, 47 lesions with a poor correspondence in the degree of stenosis between densitometric and geometric analysis (p greater than 0.01; and group B, 53 lesions with a good correspondence. Both groups were correlated with plaque characteristics (unstable or stable), following angiographic criteria. The mean degree of stenosis in all lesions, for densitometric and geometric analysis was 50.04 +/- 21.1% and x 60.66 +/- 22.1% (p less than 0.01), respectively. Unstable plaque was more frequent in group A (80.9%) than in B (17.9%) (p less than 0.0001), and stable plaque was more frequent in B (81.1%) than in A (19.1%) (p less than 0.0001). Less degree of stenosis between A (41.5 +/- 13.2) and B (61.3 +/- 16.05) was found by densitometric analysis (p less than 0.0001) but it was similar by geometric method (60.02 +/- 11.3 in A and 58.6 +/- 14.4 in B) so that the degree of stenosis in unstable plaque was lower by densitometric method. We conclude that densitometric analysis showed poor correlation with geometric analysis in unstable plaques; the difference could be due to the soft component expression of the unstable plaque.

Aged↗
PubMed1990

[Nasosinusal inverted papilloma. A case report].

The AA. report a case of inverted nasosinusal Papilloma diagnosed and treated surgically, at their Hospital, through a combined approach paralateronasale and Caldwell-Luc. Review of the bibliography.

Aged↗
PubMed1990

[Intravesical echography. I. Anatomical correlation].

The scan images of the normal bladder were obtained by intravesical ultrasonography (IVU) and the ultrasonographic-anatomic correlation were defined based on 179 procedures. Except in bladder cancer, IVU did not prove to be useful in the evaluation of other bladder conditions or adjacent structures, including gynecological disorders.

Female↗
PubMed1990

Genetics of lactic acid bacteria with special reference to lactococci.

Lactic acid bacteria play an important role in the manufacture of fermented foods. Genetic studies have made these microorganisms, particularly lactococci, accessible to genetic manipulation. The instability of key metabolic traits of lactococci has been explained by the presence of plasmid DNA species. Most genetic interest has been focused to solve the quoted instability and the sensitivity to bacteriophage infection. At the same time, gene transfer systems have been developed and specific genes with commercial significance have been identified and cloned. Lactic acid bacteria can be also used as production organisms of heterologous proteins, e.g. chymosin, lysozyme.

Bacterial Proteins↗
PubMed1990

[Early angiographic study post successful angioplasty. Predictor of late restenosis].

Consecutive prospective coronary angiographies following 24 hours were studied to find early angiographic predictors of post-PTCA restenosis in the follow-up of 71 patients who had been dilated successfully. Conventional cine coronary and quantitative digital angiography was used to analyse the degree of obstruction previous to dilatation following 24 hours and 30 minutes after the procedure. Following 24 hours, angiographic findings showed: Group A: patients having the same lumen as at immediate post-PTCA time (65.9%); Group B: patients with 20% or more immediate post-PTCA time (21.5%). Group C: patients with total obstruction of vessel (12.6%). The basal clinical conditions were similar in the three groups. The degree of basal obstruction and the clinical findings were similar in the three groups; the dilated arteries in Groups A and B were similar and total occlusion before PTCA was more frequent in Group C than in B and A; 30 minutes post PTCA lesions in group A had less residual stenosis than group B (p less than .01) and C (p = NS), this difference increased significantly (p less than .0001) at 24 hours and in the late follow-up. In the follow-up (means 6.4 months) there was total restenosis per lesion in 32.9%. In Group A, there was 8.6%; in Group B, 68.4% (p less than .0001) and in Group B plus C, 80%. Patients with more than 10% obstruction had a greater degree of restenosis (43.9%) than when the initial lesion was less than 10% (23.4%).(ABSTRACT TRUNCATED AT 250 WORDS)

Angioplasty, Balloon, Coronary↗
PubMed1989

A prospective study of a rapid method for diagnosing cytomegalovirus infections in immunosuppressed patients.

A rapid assay is described for detection of cytomegalovirus in peripheral blood lymphocytes. It consists of an indirect immunofluorescence technique for detection of cytomegalovirus antigens by means of a monoclonal antibody directed against early viral coded proteins. This assay was compared with the conventional cell culture system. Patients transplanted between December 1986 and May 1988 were studied, and of 27 patients identified, two were excluded due to early graft failure. A total of 320 blood specimens obtained were studied, and from 12 patients cytomegalovirus was isolated in at least one specimen by conventional cell culture (in total 25 specimens). Results were available with the new technique within 6 h, whereas the cell culture took an average of 13 days to develop the typical cytopathic effects changes. Sensitivity and specificity compared with that of viral isolation in conventional cell culture was 92% and 95%, respectively. This technique provides an accurate and rapid diagnosis of cytomegalovirus infections, and allows specific antiviral therapy to be started earlier.

Antibodies, Monoclonal↗
PubMed1989

[Ultrastructure of the intracellular development of bacteriophage phi C 31].

The intracellular development of the bacteriophage phi C31 in thermally induced cultures of the lysogen Streptomyces coelicolor 01 changes remarkably its cell structure. At 10 min post-induction, a big number of mesosomes are shown by the cells. At 30 min post-induction, the cytoplasm contains capsids which are still empty. At the end of the latent period mature virions are shown and immediately after, cell lysis occurs through the tip of germinative tubes. In old cultures (10 h or more) no viral progeny is detected. However, when the amino acid glycine is added to the culture medium, new virions are seen, but in smaller number than in germinating cultures. These results seem to indicate that the lysis happens at the tip of the germinative tubes probably because this is an area weakened by the preferential growth that takes place on it.

Bacteriophages↗
PubMed1988

Preliminary x-ray investigation of an orthorhombic crystal of hevein.

Hevein, a small protein from the latex of Hevea brasiliensis, has been crystallized by the vapor diffusion method using 2-methyl-2,4-pentanediol and CaCl2 as the precipitant agents. The crystals are orthorhombic space group P21212 with a = 21.88, b = 31.90, and c = 51.24 A and one molecule in the asymmetric unit. The crystals are quite stable to x-rays and suitable for a high resolution three-dimensional structure determination.

Antimicrobial Cationic Peptides↗
PubMed1988

Anatomic surgical dissection of the extraparotid portion of the facial nerve.

The direction followed by the facial nerve branches beyond their emergence from the ventral, cephalic, and caudal borders of the parotid gland up to the facial muscles has been studied by several anatomists, but no consistent description of them has been given so far. This research, based on the dissection of 30 hemifaces, studies the characteristics of those branches using three points of reference: the intertragal notch, the palpebral lateral commissure, and the labial commissure. Tables showing average length and number of branches have been computed with a statistical level of confidence of 99 percent. No fixed common pattern suitable to represent the distribution of branches of the facial nerve in a model was found, but as a rule, these branches run beneath the superficial musculoaponeurotic system (SMAS) in their path below the zygomatic arch, and approximate emergence points have been identified. In the opinion of the authors, such points may be of more surgical relevance than a theoretical pattern of arborization.

Adult↗
PubMed1988

The effect of rifampicin on the development of the Streptomyces bacteriophage phi C31.

The production of phi C31 progeny virus was inhibited by rifampicin when it was added at any time before 20 minutes after induction of the thermoinducible lysogen Streptomyces coelicolor 01. The inhibition was gradually lost as the antibiotic was being added later on until the end of the latent period, which lasts about 45 minutes. This effect was not due to resistance of transcription to rifampicin but to accumulation of intracellular virions from around 20 minutes postinduction. When a rifampicin-resistant lysogen was induced in the presence of the antibiotic, no inhibition of RNA synthesis was detected, although a smaller population of progeny than in control cultures without rifampicin was obtained. Two possible explanations of this fact are discussed.

Bacterial Proteins↗