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Biomedical subjects

A Romanella

Publications and source records attributed to A Romanella.

10 recordsLinked to original sources

Retinoblastoma. The long-term appearance of radiated intraocular tumors.

A retrospective analysis of 50 patients with retinoblastoma was undertaken to determine the appearance of intraocular retinoblastoma that had received external beam radiation a minimum of 10 years previously. Of the 91 tumors found in 59 eyes, 76 (84%) continued to be ophthalmoscopically visible after 10 years. The most common ophthalmoscopic appearance was a Type III regression pattern. The type of radiation regression pattern correlated with the pretreatment volume of the tumor. The largest tumors (mean, 10.0 disc diameter [dd]) became Type I regression patterns, whereas the smallest tumors (mean, 1.0 dd) completely disappeared. This represents the first long-term follow-up of the intraocular status of radiated retinoblastoma.

Child↗

Retinoblastoma.

Retinoblastoma, although a rare childhood cancer, is the most common primary malignant intraocular tumor of infancy and early childhood. In 75% of the cases, retinoblastoma is unilateral, and in 25% of the cases, retinoblastoma is bilateral. Presenting signs and symptoms of retinoblastoma, genetics, diagnostic tests, and their implications are reviewed in this paper. Treatment options for retinoblastoma (enucleation, external beam radiation, radioactive plaque, cryotherapy, photocoagulation, and chemotherapy) and their nursing care are discussed. Finally, second tumors such as osteosarcomas are discussed.

Cryosurgery↗

Retinoblastoma after 15 years.

Retinoblastoma, a cancer of early childhood, occurs once in 18,000 to 30,000 live births worldwide. Not only are bilateral cases diagnosed at an earlier age than unilateral cases, but bilateral cases are also associated with multifocal tumors. A ten-month-old girl was treated for bilateral retinoblastoma (the right eye was Group Ia; the left eye was Group IIIb) with 3500 rads of external beam radiation. The metastatic workup was negative. Because new tumors developed OS, a combination of photocoagulation and cryotherapy treatments were necessary. Fifteen years after treatment, the right eye had Type II regression and the left eye, Type III.

Adolescent↗

Optic nerve meningioma: a case report.

1. Primary meningiomas are slow growing, cytologically benign tumors that can invade the optic nerve, dura, or extraocular muscles, but do not metastasize. 2. Although many of the presenting signs, symptoms, and clinical patterns for primary meningioma are nonspecific, there can be a distinctive pattern. 3. Treatment depends on the patient's visual acuity, size, and location of the tumor.

Adult↗

Unusual presenting signs of retinoblastoma: a case study.

In the US, leukocoria is the most common presenting sign of retinoblastoma, and strabismus is the second most common finding. Retinoblastoma less frequently presents as an inflammatory process involving the eye or orbit, which often masks the symptoms of retinoblastoma. Children who present with leukocoria strabismus, hypopyon, heterochromia, rubeosis, hyphema, or an orbital cellulitis should be referred to an ophthalmologist for a dilated fundus examination of both eyes, under general anesthesia if necessary, to rule out the possibility of a retinoblastoma in the differential diagnosis.

Child, Preschool↗

Melanocytoma.

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Cranial Nerve Neoplasms↗

Identifying a metastatic choroidal tumor: a case study.

Amelanotic lesions of the eye are more commonly seen in metastatic disease, whereas melanomas are usually melanotic and are not associated with pain. Metastatic tumors exhibit medium to high reflectivity pattern on ultrasound A scan, whereas melanomas usually display a low to medium pattern. A patchy, diffuse interocular mass with episcleral and/or orbital involvement is consistent with metastatic tumor of the eye, whereas melanomas tend to be more localized.

Adult↗