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Biomedical subjects

A Rosenbaum

Publications and source records attributed to A Rosenbaum.

At least 19 recordsLinked to original sources
PubMed1991

Coca-Cola, caffeine, and mental deficiency: Harry Hollingworth and the Chattanooga trial of 1911.

Harry Hollingworth's 1911 investigation of the behavioral effects of caffeine is one of the earliest examples of psychological research contracted by a large corporation. The research was necessitated by a federal government suit against the Coca-Cola Company for marketing a beverage with a deleterious ingredient, namely, caffeine. Although Hollingworth's research played little role in the outcome of the Coca-Cola trials, it was important as a model of sophistication in experimental design. As such, it set a standard for psychopharmacological research. It also was particularly important in directing Hollingworth toward a life-long career in applied psychology.

Animals↗
PubMed1991

Respiratory findings among ironworkers: results from a clinical survey in the New York metropolitan area and identification of health hazards from asbestos in place at work.

Diseases associated with asbestos are prevalent in the construction trades primarily as the result of the previously widespread use of insulation materials containing asbestos in the building industry. Workers in metal related trades, who are employed at construction sites, but who do not routinely use such materials in their work, may also be at risk for asbestos hazards. To assess such risk, a clinical survey was conducted on 869 ironworkers from the New York metropolitan area. A high prevalence of abnormalities on chest radiographs was found. Three hundred and twenty nine (38%) of the examined workers had pleural abnormalities on their chest radiographs consistent with asbestos induced effects. The prevalence of radiographic abnormalities indicating interstitial lung disease was low (7%) as was the prevalence of restrictive pulmonary function impairment (7%). Association was found between forced vital capacity (FVC) and pleural abnormalities on chest radiographs. Although ex-smokers appeared to have the highest prevalence of abnormalities, regression analyses showed that duration of employment in the ironworkers' trade was the most important factor associated with them.

Asbestos↗
PubMed1991

Over- vs. undercontrolled hostility: application of the construct to the classification of maritally violent men.

The purpose of the present investigation was to evaluate the applicability of Megargee's (1967) distinction between over- and undercontrolled hostility to maritally aggressive men. Subjects were 41 men who were referred for treatment for physical marital violence. Data were derived from a written battery of self-report measures. Overcontrolled hostile men showed patterns of abuse in which violent episodes were more severe but less frequent and in which the wife was the sole target of the aggressive behavior. Undercontrolled hostile husbands were more generally aggressive and more frequently aggressive. Additionally, undercontrolled husbands were more likely than overcontrolled husbands to have witnessed violence in their families of origin and to have had rejecting mothers. Implications for the assessment and treatment of marital violence are discussed.

Adult↗
PubMed1991

[Role of percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis].

Percutaneous endoscopic gastrostomy (PEG) is an enteral nutritional assistance technique using a simple device compatible with conventional feeding and thus enabling the patient to be integrated into his or her social and familial surroundings. This inexpensive device is quickly and easily inserted under local anaesthesia. It causes little morbidity and virtually no mortality and has many advantages for patients with amyotrophic lateral sclerosis (ALS). We report the results of PEG in 28 ALS patients with bulbar involvement. Three of these patients developed minor complications during 6 consecutive months of PEG-assisted nutrition (2 had periostomial infection, 1 had mild haematemesis). There were no major complications, and mortality directly ascribable to PEG was nil. All patients put on weight or had their weight stabilized, and GEP was well accepted in all cases.

Adult↗
PubMed1989

Prevalence and stability of physical aggression between spouses: a longitudinal analysis.

Community couples (N = 272) were assessed in a longitudinal study of early marriage. More women than men reported physically aggressing against their partners at premarriage (44% vs. 31%) and 18 months (36% vs. 27%). At 30 months, men and women did not report significantly different rates of aggression (32% vs. 25%). However, using either the self-report or the partner's report, the prevalence of aggression was higher for women than men at each assessment period. Modal forms of physical aggression for both men and women were pushing, shoving, and slapping. Conditional probability analyses indicated that the likelihood of physically aggressing at 30 months given that one had engaged in such aggression before marriage and at 18 months after marriage was .72 for women and .59 for men. Furthermore, 25-30% of the recipients of physical aggression at all three assessment periods were seriously maritally discordant at 30 months.

Adult↗
PubMed1989

Prognosis of ruptured intracranial mycotic aneurysms: a review of 12 cases.

Intracranial mycotic aneurysms (IMA) occur in 1-3% of all infective endocarditis. Although spontaneous resolution was evidenced on serial angiograms in many asymptomatic cases, the prognosis, if they rupture, is reported to be worse and partly contingent on the therapeutic approach. Among 12 patients (six acute and six subacute endocarditis) with ruptured IMA, six were treated surgically and four were treated medically. Two patients died during rupture before any treatment could be started. Six patients had a sudden rupture manifested by coma, less clear consciousness seizures, hemiparesis unilateral mydriasis. CT-Scan showed intracerebral, intraventricular and subarachnoid haemorrhage. Ten angiograms showed 11 IMA. For patients with ruptured IMA, the decision for surgical treatment was made in the presence of deepening coma and extensive mass-lesion on CT-scan (one of six died in the postoperative period). Others received medical treatment (four cases: all survived) and were followed-up with serial angiographies. Of the nine patients who survived, five remained free of any disability 1-4 years later. We suggest that the prognosis of ruptured IMA (25% mortality rate) is not as bad as previously reported if surgery following angiography is performed early in the presence of deepening coma and extensive lesion.

Adolescent↗
PubMed1989

Head injury and marital aggression.

Of 31 consecutive male patients referred for evaluation of marital violence, 19 (61.3%) had histories of severe head injury. Although the relationship between child abuse and head injury did not reach an acceptable level of significance, it did indicate a trend toward a positive relationship. Alcohol abuse, reported by 48.4% of the sample, was significantly associated with head injury. Confirmation of biological etiologies in marital aggression would have implications for prevention and treatment.

Adolescent↗
PubMed1988

Quantification of thermal asymmetry. Part 2: Application in low-back pain and sciatica.

Temperature differences between the lower extremities were measured using a computerized thermometric scanning system in order to compare the degree of thermal asymmetry in 144 patients with low-back pain. The patients displayed highly significant thermal asymmetries, with the involved limb being cooler (p less than 0.001). When asymmetries exceeded 1 standard deviation from the mean temperature of homologous regions measured in 90 normal control subjects, the positive predictive value of thermometry in detecting root impingement was 94.7% and the specificity was 87.5%. These values indicate that calculation of temperature asymmetry is particularly effective in evaluating reported pain in psychosocially affected patient populations in whom the chance of positive myelography or impaired root function is low. In this group of patients, thermometric study provides physicians with important information for proper decision making. The test can be performed to avoid more invasive and probably less revealing diagnostic or exploratory surgical procedures.

Adult↗
PubMed1987

[Mammary localization of malignant non-Hodgkin's lymphomas. Apropos of 4 cases].

Mammary localizations of non-hodgkinian malignant lymphomas (NHML) are rare. They occur in three different contexts: isolated tumor of the primary mammary lymphoma, initial "first manifestation" tumor of a diffuse lymphomatous disease, or else a mammary tumor occurring during the course of a known NHML. Four cases of mammary localization of NHML are reported. A review of the literature permits to bring out the following characteristics: probable etiological role of pregnancy, clinical picture of one or several masses, uni or bilateral, evoluting rapidly, and frequently associated to inflammatory signs; false benign aspect on mammograms. Histological examination associated with a strict evaluation of the extension is fundamental in order to determine therapy and prognosis. These two factors have been considerably modified in the past two decades as it is the case for all NHML. Chemotherapy occupies an essential place in the treatment. Mammary localization of NHML is first of all a lymphomatous disease, which is often a diffuse disease before becoming a breast disease.

Adult↗
PubMed1986

beta-Endorphin/beta-lipotropin immunoreactivity in endogenous depression. Effect of dexamethasone.

This study addresses the question of whether pituitary peptides (ie, beta-endorphin) show regulatory disruption in endogenous depression and, if so, does it co-occur in the same subjects who show cortisol dysregulation. Endogenously depressed patients and psychiatric controls from three centers were evaluated, when not taking medications, and studied for plasma cortisol and beta-endorphin levels. Plasma samples were taken at four time points over one hour, on the basal day, and 16 hours after 1 mg of dexamethasone. From 33% to 69% of the endogenous patients were abnormal in their postdexamethasone cortisol levels, and from 50% to 69% were abnormal on postdexamethasone beta-endorphin values (vs 0% and 8%, respectively, for controls). When endogenous subjects were evaluated for abnormality on both cortisol and beta-endorphin, after dexamethasone, it was found that the two measures of hypothalamic-pituitary-adrenal dysfunction did not necessarily co-vary. In fact when having either abnormal beta-endorphin or cortisol levels (or both) was used as a biological marker a larger number of the endogenous patients were detected than with either measure alone. Our conclusions are as follows: Plasma beta-endorphin shows a circadian rhythm similar to that seen with corticotropin (ACTH) and is suppressable by dexamethasone. In many endogenous patients plasma beta-endorphin levels escape from dexamethasone suppression. Many of these subjects are not cortisol escapers. When abnormality of either the beta-endorphin or cortisol is considered it is clear that both levels of the hypothalamic-pituitary-adrenal axis can be dysregulated in endogenous depression.

Adolescent↗