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A Rubens-Duval

Publications and source records attributed to A Rubens-Duval.

At least 19 recordsLinked to original sources
PubMed1978

[Physiopathology of primitive arthrosis. Problems and hypotheses].

The origin and the evolution of the so-called primitive arthrosis represent two problems that hypotheses, developed by the authors, contribute to elucidate. Primitive arthrosis begins with a prearthrosic chondropathy which looks like the changes in the joint cartilage due to aging and due both to local conditions preventing the nutrition of the cartilage and to general factors causing failure of the system regulating the synthesis and the differentiation of articular tissues. These conditions are also relevant to primitive monoarthrosis, relatively rare in comparison with the frequency of secondary arthrosis and in comparison with arthrosis disease, which is the prototype of primitive polyarthrosis. The variable mixture of different local and general factors can explain the differences in evolution of primitive arthrosis, ranging from slow chondral erosion to accelerated destruction of bone and cartilage.

Arthritis↗
PubMed1975

[Histological aspects of the sarcomatous degeneration of bone in Paget's disease].

After a critical review of the literature and an enquiry based on 70 cases, the author confirms that osteogenic sarcomas and fibrosarcomas constitute the usual means of sarcomatous degeneration in bones affected by Paget's disease. Giant-cell tumours present a distinct group. The problems posed by the initial stages of the malignant transformation and the osteosarcomas with multiple centres are then discussed.

Bone Neoplasms↗
PubMed1974

[Articular manifestations of cryoglobulinemias].

Manifestations are found in the joints in 27-50 percent of patients with cryoglobulinaemia. They include arthralgia, or less frequently arthritis of distal oligo-articular topography, predominantly in the lower limbs. These manifestations consist of pure synovitis - nonexudative, nondestructive, and usually recurrent. Cold is rarely a precipitating factor. The manifestations are indicative of cryoglobulinaemia when they are associated with other symptoms of the disorder, among which Raynaud's disease and purpura of the lower limbs are the most frequent. Cryoglobulin is demonstrated only if the blood is centrifuged at 37 degrees C before being held at 4 degrees C. Different immunochemical forms of cryoglobulins exist. The list of disorders that accompany cryoglobulinaemia includes multiple myeloma, Waldenström's disease, idiopathic glomerulonephritis, and, in particular, autoimmune diseases, such as the Sjögren syndrome and disseminated lupus erythematosus. In cases of rheumatoid arthritis, cryoprecipitable proteins are found in the synovial fluid and in the serum. Almost half the cases of cryoglobulinaemia are idiopathic cryoglobulinaemias and constitute the purpura-arthralgia-asthenia-cryoglobulinaemia syndrome. Immunological studies indicate that the mixed cryoglobulins that are characteristic of the idiopathic forms, are the circulating immune complexes that are responsible for the visceral lesions. The mechanism of cryoprecipitation remains unknown. Treatment is mainly symptomatic, as immunodepressants give variable results.

Antigen-Antibody Complex↗