Biomedical subjects

A Ruiz-Torres

Publications and source records attributed to A Ruiz-Torres.

3 recordsLinked to original sources

PubMed1978

[Results concerning the sensitivity of old patients against digitalis (author's transl)].

It could be demonstrated that there was an age-dependent increase of digitalisintoxications in correlation with digitalisconcentrations in blood. This phenomenon can be explained with the frequently observed underweight in the senium. Some patients older than 70 years showed symptoms of intoxication in spite of a normal digitalisconcentration in serum. But the presented results did not demonstrate a significant difference between young and old patients concerning the sensitivity against digitalis. Therefore it is necessary to consider the bodyweight for digitalis therapy in older patients.

Age Factors↗

PubMed1977

[Hydroxylation of skin collagen in relation to age: analyses of the human skin].

The results of human skin analysis are demonstrated. It has been pointed out, that the content of hydroxyproline and hydroxylysine, in addition to the usual variation as the other aminoacids varies extensively. The extent of hydroxylation was estimated from the relation of OH-aminoacids to (not hydroxylated) each other. The determined variation of the results is most probably due to a different collagen hydroxylation within the biological dispersion. An age-related degree of hydroxylation could not be detected.

Adult↗

PubMed1977

[Age-dependent metabolism and polymerisation of collagen (author's transl)].

Investigations of collagen metabolism on the one side and of crosslinking of fibres on the other side speak for the assumption that the decrease of synthesis of collagen correlates with an increase of its crosslinking. This process can be seen in the skin of aging rats. The increase of steady crosslinks bonds represents a regulation to elongate the life-span of fibres, that means a compensation for the decreased production of new collagen.

Aging↗