PubMed HealthSearch

Biomedical subjects

A S Cheng

Publications and source records attributed to A S Cheng.

2 recordsLinked to original sources

Relative legibility study using Chinese optotypes.

Traditionally, visual acuity test charts have been constructed using the English alphabet. It is desirable to have charts made in the native language of the Chinese and Asian populations. Previous efforts in this respect have not considered the relative legibility of Chinese optotypes. In this study, twelve Chinese optotypes were constructed according to the Snellen principle and subjected to a relative legibility trial. This study provides a basis on which Chinese optotypes of near-equal legibility may be selected.

Adolescent

Immunologic changes in children with Henoch-Schonlein purpura in the acute stage.

T-lymphocyte subsets, B-lymphocyte, immunoglobulins and complement were studied in 38 children with Henoch Schonlein Purpura (HSP) in the acute stage. They had significantly lower CD3 percentage and lymphocyte blastogenesis rate, greater CD8 variation coefficient and B-lymphocyte percentage and higher levels immunoglobulins (IgA, IgG, IgM) and complement 3 than the controls. 21 (55%) of them had a low CD8 percentage. The results indicated that children with HSP had low T-lymphocyte percentages and function, increased B-lymphocyte percentage and function, high immunoglobulins, normal or elevated complement. On the other hand, no significant differences were found in the T-lymphocyte subsets values among healthy children aged 7-11 years. The normal values of T cell subsets in 35 normal controls were CD3 66-70%, CD4 37-41%, CD8 28-32%, respectively.

B-Lymphocytes