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Biomedical subjects

A S Coker

Publications and source records attributed to A S Coker.

7 recordsLinked to original sources

Spectrum of Vibrio infections in a Gulf Coast community.

Infection with Vibrio species was diagnosed in 23 patients over a 10-year period in a Gulf Coast community. Species isolated were Vibrio vulnificus, V. cholerae, V. parahaemolyticus, and V. alginolyticus. Clinical presentations included diarrhea, wound infection, and bacteremia. Gastrointestinal tract infection was infrequently diagnosed, despite the routine use of stool culture media appropriate for vibrio isolation. Bacteremic infections were severe and occurred only in patients with underlying diseases. Wound infections were complicated by tissue necrosis and required surgical debridement. In patients with underlying diseases, soft tissue infections often progressed to fatal septicemias.

Adolescent↗

Gram-negative bacillus pneumonia.

Our experience with gram-negativebacillus pneumonia (GNBP) was examined to assist us in the diagnosis and treatment of this serious condition. The patients were divided into three categories: those with primary GNBP, those with primary nosocomial GNBP, and those with superinfection GNBP. Mortality correlated highly with the severity of underlying disorders. Aspiration occurred or was suspected before most instances of primary GNBP. Tracheostomy, inhalation therapy, and aspiration were common events before development of primary nosocomial GNBP and superinfection GNBP. Half the patients survived the two primary varieties of GNBP. A striking leukocytosis developed at the onset of most cases of primary nosocomial GNBP and superinfection GNBP.

Adult↗